Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.61 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.61 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.61 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.61 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.61 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | GFER | P55789 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4347843 | 0.91 | HPGD (0.61) | HPGDALDH1A1HSD17B10CYP1A2CYP3A4 | |
| SCHEMBL4353434 | 0.84 | HPGD (0.61) | HPGDALDH1A1HSD17B10CYP1A2CYP3A4 | |
| SCHEMBL4815471 | 0.82 | HPGD (0.66) | HPGDALDH1A1HSD17B10CYP1A2CYP3A4 | |
| SCHEMBL4815481 | 0.82 | HPGD (0.66) | HPGDALDH1A1HSD17B10CYP1A2CYP3A4 | |
| SCHEMBL4345772 | 0.80 | HPGD (0.43) | HPGDALDH1A1HSD17B10CYP1A2CYP3A4 | |
| SCHEMBL108225 | 0.80 | ALDH1A1 (0.90) | HPGDALDH1A1HSD17B10CYP1A2CYP3A4 | |
| SCHEMBL4353493 | 0.80 | HPGD (0.43) | HPGDALDH1A1HSD17B10CYP1A2CYP3A4 | |
| SCHEMBL4343757 | 0.79 | HPGD (0.42) | HPGDALDH1A1HSD17B10CYP1A2CYP3A4 | |
| SCHEMBL4345617 | 0.79 | HPGD (0.42) | HPGDALDH1A1HSD17B10CYP1A2CYP3A4 | |
| SCHEMBL5970063 | 0.77 | HPGD (1.00) | HPGDALDH1A1HSD17B10CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2088149-A1 | PHARMACOLOGICALLY ACTIVE N,N'-SUBSTITUTED 3,7-DIAZABICYCLO Ý3.3.1¨NONANES, PHARMACEUTICAL COMPOSITIONS BASED THEREON AND A METHOD FOR THE USE THEREOF | Institute of Physiologically active compunds of the Russian Academy of Sciences (IPAC RAN) (RU) | 2009-08-12 | — | — | EP | claimed |
| EP-2088149-A1 | PHARMACOLOGICALLY ACTIVE N,N'-SUBSTITUTED 3,7-DIAZABICYCLO Ý3.3.1¨NONANES, PHARMACEUTICAL COMPOSITIONS BASED THEREON AND A METHOD FOR THE USE THEREOF | Institute of Physiologically active compunds of the Russian Academy of Sciences (IPAC RAN) (RU) | 2009-08-12 | — | — | EP | disclosed |