Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 14/20 | 0.52 |
| ▸ | PRKCB | P05771 | 8/20 | 0.51 |
| ▸ | PRKCA | P17252 | 4/20 | 0.48 |
| ▸ | PRKCG | P05129 | 2/20 | 0.48 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.43 |
| ▸ | CDK1 | P06493 | 2/20 | 0.43 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.43 |
| ▸ | CDK2 | P24941 | 2/20 | 0.43 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.43 |
| ▸ | CCNB3 | Q8WWL7 | 2/20 | 0.43 |
| ▸ | CNR2 | P34972 | 4/20 | 0.41 |
| ▸ | CNR1 | P21554 | 3/20 | 0.41 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.40 |
| ▸ | IDH1 | O75874 | 1/20 | 0.39 |
| ▸ | TYK2 | P29597 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4346710 | 0.97 | GSK3B (0.53) | GSK3BPRKCBPRKCAPRKCGCCNB2 | |
| SCHEMBL15524666 | 0.82 | GSK3B (0.72) | GSK3BPRKCBPRKCAPRKCGCCNB2 | |
| SCHEMBL2972351 | 0.82 | GSK3B (0.75) | GSK3BPRKCBPRKCAPRKCGCCNB2 | |
| SCHEMBL4350843 | 0.81 | GSK3B (0.52) | GSK3BPRKCBPRKCAPRKCGCCNB2 | |
| SCHEMBL2982248 | 0.78 | GSK3B (0.76) | GSK3BPRKCBPRKCAPRKCGCCNB2 | |
| SCHEMBL13204161 | 0.76 | GSK3B (0.75) | GSK3BPRKCBPRKCAPRKCGCCNB2 | |
| SCHEMBL4349101 | 0.73 | GSK3B (0.73) | GSK3BPRKCBPRKCAPRKCGCCNB2 | |
| SCHEMBL13204159 | 0.70 | GSK3B (0.57) | GSK3BPRKCBPRKCAPRKCGCCNB2 | |
| SCHEMBL20688049 | 0.69 | GSK3B (0.56) | GSK3BPRKCBPRKCAPRKCGCCNB2 | |
| SCHEMBL2984397 | 0.68 | GSK3B (0.82) | GSK3BPRKCBPRKCAPRKCGCCNB2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9845460-B2 | Treatment of pluripotent cells | JANSSEN BIOTECH, INC. (US) | 2017-12-19 | — | — | US | disclosed |
| US-20140080210-A1 | Treatment of Pluripotent Cells | JANSSEN BIOTECH, INC. (US) | 2014-03-20 | — | — | US | disclosed |
| US-8623648-B2 | Treatment of pluripotent cells | JANSSEN BIOTECH, INC. (US) | 2014-01-07 | — | — | US | disclosed |
| US-20090325293-A1 | TREATMENT OF PLURIPOTENT CELLS | JANSSEN BIOTECH, INC. | 2009-12-31 | — | — | US | disclosed |