Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSK3B | P49841 | 11/20 | 0.73 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.73 |
| ▸ | CDK1 | P06493 | 1/20 | 0.73 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.73 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.73 |
| ▸ | CDK2 | P24941 | 1/20 | 0.73 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.73 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.73 |
| ▸ | PRKCB | P05771 | 7/20 | 0.50 |
| ▸ | PRKCA | P17252 | 4/20 | 0.50 |
| ▸ | PRKCG | P05129 | 2/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4766853 | 0.84 | GSK3B (1.00) | GSK3BCCNB2CDK1CCNB1CCNA2 | |
| SCHEMBL15524666 | 0.78 | GSK3B (0.72) | GSK3BCCNB2CDK1CCNB1CCNA2 | |
| SCHEMBL4346710 | 0.74 | GSK3B (0.53) | GSK3BCCNB2CDK1CCNB1CCNA2 | |
| SCHEMBL4346191 | 0.73 | GSK3B (0.52) | GSK3BCCNB2CDK1CCNB1CCNA2 | |
| SCHEMBL4350843 | 0.71 | GSK3B (0.52) | GSK3BCCNB2CDK1CCNB1CCNA2 | |
| SCHEMBL4337838 | 0.67 | GSK3B (1.00) | GSK3BCCNB2CDK1CCNB1CCNA2 | |
| SCHEMBL2983502 | 0.66 | GSK3B (1.00) | GSK3BCCNB2CDK1CCNB1CCNA2 | |
| SCHEMBL5451155 | 0.66 | SMN1; SMN2 (0.52) | GSK3BCCNB2CDK1CCNB1CCNA2 | |
| SCHEMBL4338729 | 0.66 | GSK3B (1.00) | GSK3BCCNB2CDK1CCNB1CCNA2 | |
| SCHEMBL5454101 | 0.66 | POLB (0.51) | GSK3BCCNB2CDK1CCNB1CCNA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9845460-B2 | Treatment of pluripotent cells | JANSSEN BIOTECH, INC. (US) | 2017-12-19 | — | — | US | disclosed |
| US-20140080210-A1 | Treatment of Pluripotent Cells | JANSSEN BIOTECH, INC. (US) | 2014-03-20 | — | — | US | disclosed |
| US-8623648-B2 | Treatment of pluripotent cells | JANSSEN BIOTECH, INC. (US) | 2014-01-07 | — | — | US | disclosed |
| US-20090325293-A1 | TREATMENT OF PLURIPOTENT CELLS | JANSSEN BIOTECH, INC. | 2009-12-31 | — | — | US | disclosed |