Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 11/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 6/20 | 0.51 |
| ▸ | DRD3 | P35462 | 3/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.51 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.51 |
| ▸ | ADRA1D | P25100 | 2/20 | 0.51 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.51 |
| ▸ | ADRA1B | P35368 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | HTR1A | P08908 | 1/20 | 0.51 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.51 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.51 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.51 |
| ▸ | HTR2B | P41595 | 1/20 | 0.51 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.51 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4326693 | 1.00 | ADRB2 (0.53) | ADRB2ADRB1DRD3CYP2D6ADRA2A | |
| SCHEMBL2797646 | 1.00 | ADRB2 (0.53) | ADRB2ADRB1DRD3CYP2D6ADRA2A | |
| SCHEMBL2794135 | 0.89 | ADRB2 (0.46) | ADRB2ADRB1CYP2D6ADRB3 | |
| SCHEMBL2794305 | 0.85 | ADRB2 (0.60) | ADRB2ADRB1DRD3CYP2D6ADRA1D | |
| SCHEMBL13170538 | 0.85 | ADRB2 (0.60) | ADRB2ADRB1DRD3CYP2D6ADRA1D | |
| SCHEMBL2794303 | 0.85 | ADRB2 (0.60) | ADRB2ADRB1DRD3CYP2D6ADRA1D | |
| SCHEMBL2797641 | 0.85 | ADRB2 (0.75) | ADRB2ADRB1DRD3CYP2D6ADRA1A | |
| SCHEMBL4346835 | 0.85 | ADRB2 (0.75) | ADRB2ADRB1DRD3CYP2D6ADRA1A | |
| SCHEMBL2797643 | 0.85 | ADRB2 (0.75) | ADRB2ADRB1DRD3CYP2D6ADRA1A | |
| SCHEMBL2796159 | 0.82 | ADRB2 (0.46) | ADRB2ADRB1KDM4EADRB3GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2057122-A1 | DERIVATIVES OF 4-(2-AMINO-1-HYDROXYETHYL)PHENOL AS AGONISTS OF THE 2 ADRENERGIC RECEPTOR | Laboratorios Almirall, S.A. (ES) | 2009-05-13 | — | — | EP | claimed |
| WO-2008046598-A1 | DERIVATIVES OF 4-(2-AMINO-1-HYDROXYETHYL)PHENOL AS AGONISTS OF THE β2 ADRENERGIC RECEPTOR | LABORATORIOS ALMIRALL, S.A. (ES) | 2008-04-24 | — | — | WO | claimed |