Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 4/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.49 |
| ▸ | KCNA5 | P22460 | 2/20 | 0.49 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.47 |
| ▸ | DRD1 | P21728 | 3/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.47 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | HRH1 | P35367 | 2/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.47 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.47 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.47 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5379223 | 0.98 | CYP2D6 (0.55) | CYP2D6CYP2C19KCNH2KCNA5CHRM2 | |
| SCHEMBL6439932 | 0.89 | CYP2D6 (0.53) | CYP2D6CYP2C19KCNH2KCNA5CHRM2 | |
| SCHEMBL13220768 | 0.85 | CYP2D6 (0.50) | CYP2D6CYP2C19KCNH2KCNA5CHRM2 | |
| SCHEMBL11260775 | 0.85 | CYP2D6 (0.50) | CYP2D6CYP2C19KCNH2KCNA5CHRM2 | |
| SCHEMBL4445537 | 0.84 | CYP2D6 (0.72) | CYP2D6CYP2C19KCNH2CHRM2ADRA2A | |
| SCHEMBL2760196 | 0.83 | CYP2D6 (0.55) | CYP2D6CYP2C19KCNH2KCNA5CHRM2 | |
| Alcohol SCHEMBL7553089 | 0.83 | POLB (0.54) | CYP2D6CYP2C19KCNH2CHRM2ADRA2A | |
| SCHEMBL14748423 | 0.83 | CYP2D6 (0.51) | CYP2D6CYP2C19KCNH2KCNA5CHRM2 | |
| SCHEMBL844392 | 0.82 | CYP2D6 (0.55) | CYP2D6CYP2C19KCNH2CHRM2ADRA2A | |
| SCHEMBL440638 | 0.82 | POLB (0.58) | CYP2D6CYP2C19KCNH2CHRM2ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107955107-B | Method for preparing star polyacrylamide by single electron transfer living radical polymerization | 东北石油大学 | 2020-12-29 | — | — | CN | claimed |
| US-11666658-B2 | Rifamycin analogs and antibody-drug conjugates thereof | Regeneran Pharmaceuticals, Inc. (US) | 2023-06-06 | — | — | US | disclosed |
| CN-107955107-B | Method for preparing star polyacrylamide by single electron transfer living radical polymerization | 东北石油大学 | 2020-12-29 | — | — | CN | disclosed |
| US-20200368361-A1 | RIFAMYCIN ANALOGS AND ANTIBODY-DRUG CONJUGATES THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2020-11-26 | — | — | US | disclosed |
| WO-2020132483-A1 | RIFAMYCIN ANALOGS AND ANTIBODY-DRUG CONJUGATES THEREOF | REGENERON PHARMACEUTICALS, INC. (US) | 2020-06-25 | — | — | WO | disclosed |
| EP-2596062-B1 | SET-LRP POLYMERIZATION OF ACRYLATES IN THE PRESENCE OF ACIDS | ROHM & HAAS (US) | 2019-09-18 | — | — | EP | disclosed |
| US-10273314-B2 | Set-LRP polymerization of acrylates in the presence of acids | ROHM AND HAAS COMPANY (US) | 2019-04-30 | — | — | US | disclosed |
| US-20130245216-A1 | SET-LRP POLYMERIZATION OF ACRYLATES IN THE PRESENCE OF ACIDS | THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA (US) | 2013-09-19 | — | — | US | disclosed |
| EP-2596062-A1 | SET-LRP POLYMERIZATION OF ACRYLATES IN THE PRESENCE OF ACIDS | Rohm and Haas Company (US) | 2013-05-29 | — | — | EP | disclosed |
| CN-103119098-A | SET-LRP Polymerization of Acrylic Compounds in the Presence of Acid | ROHM & HAAS | 2013-05-22 | — | — | CN | disclosed |
| WO-2012012705-A1 | SET-LRP POLYMERIZATION OF ACRYLATES IN THE PRESENCE OF ACIDS | ROHM AND HAAS COMPANY (US) | 2012-01-26 | — | — | WO | disclosed |
| EP-0949230-B1 | PROCESSES FOR PRODUCING ALKENYL-SUBSTITUTED AROMATIC HYDROCARBONS | SUMITOMO CHEMICAL CO (JP) | 2005-07-27 | — | — | EP | disclosed |
| US-6403852-B1 | CATALYTIC ALKENYLATION OF ALKYL-SUBSTITUTED AROMATIC HYDROCARBON HAVING HYDROGEN ATOM AT ALPHA-POSITION OF SIDE CHAIN THEREOF WITH CONJUGATED DIENE | SUMITOMO CHEMICAL CO., LIMITED (JP) | 2002-06-11 | — | — | US | disclosed |
| EP-0949230-A1 | PROCESSES FOR PRODUCING ALKENYL-SUBSTITUTED AROMATIC HYDROCARBONS | SUMITOMO CHEMICAL COMPANY LIMITED (JP) | 1999-10-13 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200368361-A1 | RIFAMYCIN ANALOGS AND ANTIBODY-DRUG CONJUGATES THEREOF | ASGR1, CUTA, SRPRA | CYP2D6 1391/4885CYP2C19 2413/4885KCNH2 4322/4885 |
| US-11666658-B2 | Rifamycin analogs and antibody-drug conjugates thereof | ASGR1, CUTA, SRPRA | CYP2D6 1391/4885CYP2C19 2413/4885KCNH2 4322/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.