⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5142057 | 0.97 | EPHX1 (0.55) | — | |
| SCHEMBL5249016 | 0.97 | EPHX1 (0.55) | — | |
| SCHEMBL7453221 | 0.97 | EPHX1 (0.55) | — | |
| SCHEMBL1770447 | 0.97 | EPHX1 (0.55) | — | |
| SCHEMBL16892582 | 0.97 | EPHX1 (0.55) | — | |
| SCHEMBL198272 | 0.97 | — | — | |
| SCHEMBL5246477 | 0.97 | EPHX1 (0.55) | — | |
| SCHEMBL5073915 | 0.97 | EPHX1 (0.55) | — | |
| SCHEMBL6235646 | 0.97 | EPHX1 (0.55) | — | |
| SCHEMBL997426 | 0.97 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 401 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114450283-B | 3, 6-Diamino-pyridazin-3-yl derivatives, pharmaceutical compositions containing them and their use as pro-apoptotic agents | 法国施维雅药厂 | 2024-05-07 | — | — | CN | claimed |
| CN-117586262-A | Nucleoside analogues and uses thereof | 苏州旺山旺水生物医药有限公司 | 2024-02-23 | — | — | CN | claimed |
| EP-4003988-A1 | 3,6-DIAMINO-PYRIDAZIN-3-YL DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS PRO-APOPTOTIC AGENTS | Les Laboratoires Servier (FR) | 2022-06-01 | — | — | EP | claimed |
| CN-114450283-A | 3, 6-diamino-pyridazin-3-yl derivatives, pharmaceutical compositions containing them and their use as pro-apoptotic agents | 法国施维雅药厂 | 2022-05-06 | — | — | CN | claimed |
| WO-2021018857-A1 | 3,6-DIAMINO-PYRIDAZIN-3-YL DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS PRO-APOPTOTIC AGENTS | LES LABORATOIRES SERVIER (FR) | 2021-02-04 | — | — | WO | claimed |
| CN-110256432-A | Inhibit the polycyclic compound of MNK1 and MNK2 | 诺沃斯达药业有限公司 | 2019-09-20 | — | — | CN | claimed |
| WO-2019154133-A1 | DIOXAZOLINE COMPOUND, PREPARATION METHOD THEREFOR, AND USES THEREOF | 北京赛特明强医药科技有限公司 | 2019-08-15 | — | — | WO | claimed |
| CN-105175349-A | Phenyl substituted triazine compounds adopted as EGFR inhibitor, and applications thereof | NANJING SANHOME PHARMACEUTICAL CO LTD | 2015-12-23 | — | — | CN | claimed |
| CN-104341416-A | Protein tyrosine kinase inhibitor and application thereof | NANJING SANHOME PHARMACEUTICAL CO LTD | 2015-02-11 | — | — | CN | claimed |
| WO-2011078795-A1 | BRIDGED MORPHOLINO SUBSTITUTED PURINES | S*BIO PTE LTD (SG) | 2011-06-30 | — | — | WO | claimed |
| WO-2004103282-A2 | COMPOUNDS, COMPOSITIONS AND METHODS | CYTOKINETICS, INC. (US) | 2004-12-02 | — | — | WO | claimed |
| WO-2004091547-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC (US) | 2004-10-28 | — | — | WO | claimed |
| US-20040209926-A1 | Polyamine analogs that activate antizyme frameshifting | MEDIQUEST THERAPEUTICS, INC. | 2004-10-21 | — | — | US | claimed |
| US-20040082638-A1 | Compounds, compositions and methods | CYTOKINETICS, INC. | 2004-04-29 | — | — | US | claimed |
| WO-2004032879-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2004-04-22 | — | — | WO | claimed |
| US-20040058954-A1 | Polyamine analogs that activate antizyme framshifting | MEDIQUEST THERAPEUTICS, INC. | 2004-03-25 | — | — | US | claimed |
| EP-1379577-A1 | CONTROLLING SOLAR RADIATION IN SAFETY GLASS LAMINATES | Solutia Inc. (US) | 2004-01-14 | — | — | EP | claimed |
| WO-2003088903-A2 | COMPOUNDS, COMPOSITIONS, AND METHODS | CYTOKINETICS, INC. (US) | 2003-10-30 | — | — | WO | claimed |
| WO-2002077081-A1 | CONTROLLING SOLAR RADIATION IN SAFETY GLASS LAMINATES | SOLUTIA, INC. (US) | 2002-10-03 | — | — | WO | claimed |
| EP-0281731-A2 | 1-Aminomethyl-3-aryl-4-cyano-pyrroles | BAYER AG (DE) | 1988-09-14 | — | — | EP | claimed |