Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.35 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.35 |
| ▸ | ABCC1 | P33527 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3950113 | 0.86 | ALDH1A1 (0.54) | MAPTALDH1A1L3MBTL1KDM4EMEN1 | |
| SCHEMBL3119104 | 0.84 | MAPT (0.55) | MAPTALDH1A1L3MBTL1KDM4EMEN1 | |
| SCHEMBL4158477 | 0.82 | MAPT (0.60) | MAPTALDH1A1L3MBTL1KDM4EMEN1 | |
| SCHEMBL3950434 | 0.79 | ALDH1A1 (0.64) | MAPTALDH1A1L3MBTL1KDM4EMEN1 | |
| SCHEMBL7992745 | 0.79 | MAPT (0.55) | MAPTALDH1A1L3MBTL1KDM4EMEN1 | |
| SCHEMBL3950920 | 0.78 | ALDH1A1 (0.62) | MAPTALDH1A1L3MBTL1KDM4EMEN1 | |
| SCHEMBL4199731 | 0.78 | ALDH1A1 (0.42) | MAPTALDH1A1L3MBTL1KMT2A | |
| SCHEMBL4347559 | 0.78 | ALDH1A1 (0.49) | MAPTALDH1A1L3MBTL1KDM4EMEN1 | |
| SCHEMBL3950431 | 0.77 | MAPT (0.60) | MAPTALDH1A1L3MBTL1KDM4EMEN1 | |
| SCHEMBL4211551 | 0.76 | MAPT (0.59) | MAPTALDH1A1L3MBTL1KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009019508-A1 | CALCIUM ION CHANNEL MODULATORS & USES THEREOF | LECTUS THERAPEUTICS LIMITED (GB) | 2009-02-12 | — | — | WO | disclosed |