Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 8/20 | 0.36 |
| ▸ | GRIK2 | Q13002 | 5/20 | 0.36 |
| ▸ | GRIA2 | P42262 | 2/20 | 0.36 |
| ▸ | GRIA4 | P48058 | 2/20 | 0.36 |
| ▸ | GRIK3 | Q13003 | 2/20 | 0.36 |
| ▸ | GRIK5 | Q16478 | 2/20 | 0.36 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5072674 | 0.85 | GRIK1 (0.39) | GRIK1GRIK2GRIA2GRIA4GRIK3 | |
| SCHEMBL9158686 | 0.80 | GRIK1 (0.34) | GRIK1GRIK2GRIA2GRIA4GRIK3 | |
| SCHEMBL2139645 | 0.78 | GRIK1 (0.56) | GRIK1GRIK2GRIA2GRIA4GRIK3 | |
| SCHEMBL2139638 | 0.78 | GRIK1 (0.56) | GRIK1GRIK2GRIA2GRIA4GRIK3 | |
| SCHEMBL5707879 | 0.76 | GRIK1 (0.39) | GRIK1GRIK2GRIA2GRIA4GRIK3 | |
| SCHEMBL10937503 | 0.74 | KDM4E (0.48) | GRIK1GRIK2GRIA2GRIA4GRIK3 | |
| SCHEMBL10937515 | 0.74 | KDM4E (0.48) | GRIK1GRIK2GRIA2GRIA4GRIK3 | |
| SCHEMBL320056 | 0.74 | GRIK1 (0.38) | GRIK1GRIK2GRIA2GRIA4GRIK3 | |
| SCHEMBL11802504 | 0.74 | KDM4E (0.48) | GRIK1GRIK2GRIA2GRIA4GRIK3 | |
| SCHEMBL2821465 | 0.73 | GRIK1 (0.41) | GRIK1GRIK2GRIA2GRIA4GRIK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2050457-B1 | METHOD OF REMOVING ABNORMAL PRION FROM BLOOD PREPARATION | ASAHI KASEI MEDICAL CO LTD (JP) | 2012-06-27 | — | — | EP | claimed |
| EP-1473310-B1 | LEUKOCYTE REMOVAL FILTER COMPRISING A POLYMER COATING | ASAHI KASEI MEDICAL CO LTD (JP) | 2009-03-18 | — | — | EP | claimed |
| EP-2050457-B1 | METHOD OF REMOVING ABNORMAL PRION FROM BLOOD PREPARATION | ASAHI KASEI MEDICAL CO LTD (JP) | 2012-06-27 | — | — | EP | disclosed |
| US-4074041-A | ADDING STRONG ACID SALT OF CALCIUM, MAGNESIUM OR BARIUM | MITSUBISHI CHEMICAL INDUSTRIES LIMITED (JA) | 1978-02-14 | — | — | US | disclosed |