SCHEMBL434807

SCHEMBL434807

CCCC(C(=O)c1ccccc1)C(=O)c1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MDM2 Q00987 1/20 0.57
SLC6A2 P23975 1/20 0.56
SLC6A3 Q01959 1/20 0.56
PGR P06401 1/20 0.52
ADRA2A P08913 1/20 0.52
ADRA2B P18089 1/20 0.52
HTR2A P28223 1/20 0.52
HRH1 P35367 1/20 0.52
KCNH2 Q12809 1/20 0.52
NPC1 O15118 2/20 0.49
RAB9A P51151 2/20 0.49
MAPT P10636 1/20 0.49
MAPK1 P28482 1/20 0.49
HTT P42858 1/20 0.49
ATM Q13315 1/20 0.49
CES2 O00748 5/20 0.47
CES1 P23141 5/20 0.47
TDP1 Q9NUW8 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
PRSS1 P07477 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL517168 0.94 MDM2 (0.55) MDM2SLC6A2SLC6A3PGRADRA2A
SCHEMBL9049808 0.92 MDM2 (0.53) MDM2SLC6A2SLC6A3PGRADRA2A
SCHEMBL10606306 0.89 MDM2 (0.50) MDM2SLC6A2SLC6A3PGRADRA2A
SCHEMBL504212 0.88 MDM2 (0.53) MDM2SLC6A2SLC6A3PGRADRA2A
SCHEMBL7066806 0.86 MDM2 (0.52) MDM2SLC6A2SLC6A3PGRADRA2A
SCHEMBL23306717 0.86 KMT2A (0.50) MDM2SLC6A2SLC6A3PGRADRA2A
SCHEMBL12003491 0.86 MEN1 (0.53) MDM2SLC6A2SLC6A3PGRADRA2A
SCHEMBL10456426 0.85 CES2 (0.53) MDM2SLC6A2SLC6A3PGRADRA2A
SCHEMBL30979218 0.85 CES2 (0.53) MDM2SLC6A2SLC6A3PGRADRA2A
SCHEMBL27836181 0.85 CES2 (0.53) MDM2SLC6A2SLC6A3PGRADRA2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1138743-C 1, 3-diketone compound ض� 2004-02-18 CN claimed
JP-3328744-B2 2002-09-30 JP claimed
EP-0686085-A4 PROCESS OF MAKING MICROPOROUS PPS MEMBRANES DOW CHEMICAL CO (US) 1996-03-13 EP claimed
EP-0686085-A1 PROCESS OF MAKING MICROPOROUS PPS MEMBRANES THE DOW CHEMICAL COMPANY (US) 1995-12-13 EP claimed
EP-0682591-A1 PROCESS OF MAKING MICROPOROUS PPS MEMBRANES THE DOW CHEMICAL COMPANY (US) 1995-11-22 EP claimed
WO-1994017985-A1 PROCESS OF MAKING MICROPOROUS PPS MEMBRANES THE DOW CHEMICAL COMPANY (US) 1994-08-18 WO claimed
WO-1994017974-A1 PROCESS OF MAKING MICROPOROUS PPS MEMBRANES THE DOW CHEMICAL COMPANY (US) 1994-08-18 WO claimed
EP-2384193-B1 VITAMIN D PROMOTING SUNSCREEN ARMSTRONG ERNEST T (US) 2025-08-06 EP disclosed
EP-3226836-A1 VISCOSITY MODIFICATION OF ORGANIC PHASE CONTAINING COMPOSITIONS Lubrizol Advanced Materials, Inc. (US) 2017-10-11 EP disclosed
US-9724544-B2 Vitamin D promoting sunscreen Armstrong, Ernest T. (US) 2017-08-08 US disclosed
WO-2016090081-A1 VISCOSITY MODIFICATION OF ORGANIC PHASE CONTAINING COMPOSITIONS LUBRIZOL ADVANCED MATERIALS, INC. (US) 2016-06-09 WO disclosed
EP-2595598-A2 TOPICAL USE OF STEVIOL OR DERIVATIVES IN HAIR CARE DSM IP Assets B.V. (NL) 2013-05-29 EP disclosed
WO-2012010624-A2 TOPICAL USE OF STEVIOL OR DERIVATIVES IN HAIR CARE DSM IP ASSETS B.V. (NL) 2012-01-26 WO disclosed
EP-0504268-A4 PHOTOPROTECTIVE COMPOSITIONS 1993-04-21 EP disclosed
EP-0596876-A4 CHELATOR COMPOSITIONS COMPRISING ALPHA-DIAMINE COMPOUNDS. PROCTER & GAMBLE (US) 1993-03-01 EP disclosed
EP-0504268-A1 PHOTOPROTECTIVE COMPOSITIONS RICHARDSON-VICKS, INC. (US) 1992-09-23 EP disclosed
WO-1991016035-A1 CHELATOR COMPOSITIONS COMPRISING ALPHA-DIAMINE COMPOUNDS THE PROCTER & GAMBLE COMPANY (US) 1991-10-31 WO disclosed
WO-1991007944-A1 PHOTOPROTECTIVE COMPOSITIONS RICHARDSON-VICKS, INC. (US) 1991-06-13 WO disclosed
EP-0313303-A2 Photoprotection compositions comprising tocopherol sorbate and an anti-inflammatory agent THE PROCTER & GAMBLE COMPANY (US) 1989-04-26 EP disclosed
EP-0313305-A2 Photoprotection compositions comprising chelating agents THE PROCTER & GAMBLE COMPANY (US) 1989-04-26 EP disclosed