SCHEMBL4348128

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4334638	0.90	HPGD (0.42)	ALDH1A1PKMHPGDHSD17B10MEN1
	SCHEMBL4345594	0.89	HPGD (0.42)	ALDH1A1PKMHPGDHSD17B10MEN1
	SCHEMBL4334956	0.87	HPGD (0.53)	ALDH1A1PKMHPGDHSD17B10MEN1
	SCHEMBL4332464	0.86	CSNK1D (0.41)	ALDH1A1PKMHPGDHSD17B10MEN1
	SCHEMBL4341438	0.83	TTK (0.51)	ALDH1A1HPGDHSD17B10MEN1KMT2A
	SCHEMBL4332230	0.80	MAPT (0.44)	SMN1; SMN2ROCK2ROCK1NTRK1MAPT
	SCHEMBL4340568	0.79	HPGD (0.56)	ALDH1A1HPGDMEN1KMT2ASMN1; SMN2
	SCHEMBL4333958	0.79	HPGD (0.56)	ALDH1A1HPGDMEN1KMT2ASMN1; SMN2
	SCHEMBL2861181	0.78	MAP2K4 (0.51)	ALDH1A1HPGDNTRK1KDM4EMAPK1
	SCHEMBL4336101	0.78	HPGD (0.57)	ALDH1A1PKMHPGDMEN1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.