SCHEMBL4332464

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4332115	0.90	CSNK1D (0.43)	CSNK1DHPGDHSD17B10SMN1; SMN2MAPT
	SCHEMBL4340581	0.89	CSNK1D (0.42)	CSNK1DHPGDHSD17B10SMN1; SMN2ROCK2
	SCHEMBL4348128	0.86	ALDH1A1 (0.45)	HPGDHSD17B10SMN1; SMN2ROCK2ROCK1
	SCHEMBL4334956	0.85	HPGD (0.53)	HPGDHSD17B10SMN1; SMN2L3MBTL1MAPT
	SCHEMBL4341438	0.81	TTK (0.51)	HPGDHSD17B10SMN1; SMN2ROCK2ROCK1
	SCHEMBL4334043	0.79	PTGDR2 (0.42)	CSNK1DHPGDHSD17B10SMN1; SMN2ROCK2
	SCHEMBL4332230	0.78	MAPT (0.44)	SMN1; SMN2ROCK2ROCK1NTRK1MAPT
	SCHEMBL4340568	0.77	HPGD (0.56)	HPGDSMN1; SMN2ROCK2L3MBTL1MEN1
	SCHEMBL4333958	0.77	HPGD (0.56)	HPGDSMN1; SMN2ROCK2L3MBTL1MEN1
	SCHEMBL2861181	0.76	MAP2K4 (0.51)	HPGDNTRK1KDM4EALDH1A1MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.