Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 7/20 | 0.57 |
| ▸ | PPARG | P37231 | 7/20 | 0.57 |
| ▸ | PPARD | Q03181 | 7/20 | 0.57 |
| ▸ | PPARA | Q07869 | 7/20 | 0.57 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.57 |
| ▸ | TSHR | P16473 | 4/20 | 0.57 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.57 |
| ▸ | FABP4 | P15090 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.57 |
| ▸ | TLR2 | O60603 | 2/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.57 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.57 |
| ▸ | ESR1 | P03372 | 1/20 | 0.57 |
| ▸ | PDE4A | P27815 | 1/20 | 0.57 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL573131 | 0.96 | GPR84 (0.63) | GPR84PPARGPPARDPPARAHDAC11 | |
| Decanoic Acid SCHEMBL9956867 | 0.96 | GPR84 (0.63) | GPR84PPARGPPARDPPARAHDAC11 | |
| Palmitic Acid SCHEMBL30142631 | 0.96 | GPR84 (0.63) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL27998637 | 0.96 | GPR84 (0.63) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL28051852 | 0.96 | GPR84 (0.63) | GPR84PPARGPPARDPPARAHDAC11 | |
| Decanoic Acid SCHEMBL23121586 | 0.93 | GPR84 (0.63) | GPR84PPARGPPARDPPARAHDAC11 | |
| Octanoic Acid SCHEMBL757249 | 0.93 | GPR84 (0.63) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL4900334 | 0.93 | GPR84 (0.57) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL5069302 | 0.92 | GPR84 (0.61) | GPR84PPARGPPARDPPARAHDAC11 | |
| SCHEMBL31099564 | 0.92 | GPR84 (0.61) | GPR84PPARGPPARDPPARAHDAC11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2762129-B1 | COSMETIC COMPOSITION AND COSMETIC | NISSHIN OILLIO GROUP LTD (JP) | 2019-08-07 | — | — | EP | disclosed |
| EP-2762129-A1 | COSMETIC COMPOSITION AND COSMETIC | The Nisshin Oillio Group, Ltd. (JP) | 2014-08-06 | — | — | EP | disclosed |
| US-8309109-B2 | Cosmetic and method for production thereof | HAKUTO CO., LTD. (JP) | 2012-11-13 | — | — | US | disclosed |
| US-20090280149-A1 | Cosmetic and Method for Production Thereof | TELEFONAKTIEBOLAGET LM ERICSSON (PUBL) (SE) | 2009-11-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090280149-A1 | Cosmetic and Method for Production Thereof | CD44, UGCG, FUCA1 | GPR84 1087/4885PPARG 1253/4885PPARD 1891/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.