SCHEMBL4348223

SCHEMBL4348223

O=P(O)(O)O[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)[C@@H](O)[C@]1(OP(=O)(O)O)P(=O)(O)O

nearest known ligand 0.56

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ITPR3 Q14573 10/20 0.56
ITPR2 Q14571 5/20 0.41
ITPR1 Q14643 5/20 0.41
INPP5A Q14642 4/20 0.41
SMPD1 P17405 1/20 0.38
INPPL1 O15357 1/20 0.35
AKT1 P31749 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28098213 0.66 ITPR3 (0.44) ITPR3ITPR2ITPR1INPP5ASMPD1
SCHEMBL113869 0.66 ITPR3 (0.44) ITPR3ITPR2ITPR1INPP5ASMPD1
SCHEMBL27855801 0.66 ITPR3 (0.44) ITPR3ITPR2ITPR1INPP5ASMPD1
SCHEMBL27741095 0.65 ITPR3 (0.42) ITPR3ITPR2ITPR1INPP5ASMPD1
Ammonia Solution, Strong SCHEMBL27766612 0.65 ITPR3 (0.42) ITPR3ITPR2ITPR1INPP5ASMPD1
SCHEMBL5011450 0.65 ITPR3 (0.42) ITPR3ITPR2ITPR1INPP5ASMPD1
SCHEMBL10689051 0.65 ITPR3 (0.42) ITPR3ITPR2ITPR1INPP5ASMPD1
SCHEMBL27684278 0.63 ITPR3 (0.41) ITPR3ITPR2ITPR1INPP5ASMPD1
SCHEMBL15689362 0.63 ITPR3 (0.42) ITPR3ITPR2ITPR1INPP5ASMPD1
Phytic Acid SCHEMBL3742110 0.61 ITPR3 (0.89) ITPR3ITPR2ITPR1INPP5ASMPD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009052186-A1 METABOLOMICS-BASED IDENTIFICATION OF DISEASE-CAUSING AGENTS GEORGIA TECH RESEARCH CORPORATION (US) 2009-04-23 WO disclosed