Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 20/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2848786 | 0.92 | P2RX3 (0.67) | P2RX3 | |
| SCHEMBL2846526 | 0.92 | P2RX3 (0.64) | P2RX3 | |
| SCHEMBL4351809 | 0.91 | P2RX3 (0.70) | P2RX3 | |
| SCHEMBL4355255 | 0.89 | P2RX3 (0.56) | P2RX3 | |
| SCHEMBL4344498 | 0.88 | P2RX3 (0.66) | P2RX3 | |
| SCHEMBL4347403 | 0.88 | P2RX3 (0.66) | P2RX3 | |
| SCHEMBL2847636 | 0.88 | P2RX3 (0.66) | P2RX3 | |
| SCHEMBL2849770 | 0.88 | P2RX3 (0.65) | P2RX3 | |
| SCHEMBL4348277 | 0.87 | P2RX3 (0.66) | P2RX3 | |
| SCHEMBL4346177 | 0.86 | P2RX3 (0.62) | P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2136639-A1 | PYRID-2-YL FUSED HETEROCYCLIC COMPOUNDS, AND COMPOSITIONS AND USES THEREOF | Renovis, Inc. (US) | 2009-12-30 | — | — | EP | disclosed |
| WO-2008123963-A1 | PYRID-2-YL FUSED HETEROCYCLIC COMPOUNDS, AND COMPOSITIONS AND USES THEREOF | RENOVIS, INC. (US) | 2008-10-16 | — | — | WO | disclosed |