SCHEMBL43499

SCHEMBL43499

[N-]=[N+]=CC(=O)OC(F)(F)c1ccc(F)c(F)c1F

nearest known ligand 0.33

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CES2 O00748 1/20 0.33
CES1 P23141 1/20 0.33
NPSR1 Q6W5P4 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
MEN1 O00255 1/20 0.30
ALDH1A1 P00352 1/20 0.30
HTT P42858 1/20 0.30
KMT2A Q03164 1/20 0.30
HIF1A Q16665 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL43430 0.81 NPSR1 (0.38) CES2CES1NPSR1CYP1A2CYP2C9
SCHEMBL948916 0.80 CES2 (0.35) CES2CES1ALDH1A1
SCHEMBL28309363 0.77 CES2 (0.41) CES2CES1ALDH1A1
SCHEMBL8626931 0.77 CES2 (0.41) CES2CES1ALDH1A1
SCHEMBL28223430 0.76 CES2 (0.39) CES2CES1ALDH1A1
SCHEMBL5017691 0.74 CES2 (0.38) CES2CES1
SCHEMBL11867731 0.74 CES2 (0.38) CES2CES1
SCHEMBL3691325 0.73 CES2 (0.37) CES2CES1ALDH1A1
Acetic Acid SCHEMBL4207571 0.72 CES2 (0.36) CES2CES1ALDH1A1
Acetic Acid SCHEMBL2454949 0.72 CES2 (0.36) CES2CES1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011157444-A1 FUNCTIONALIZED MATERIALS BY CATALYZED CARBENE COPOLYMERIZATION STICHTING DUTCH POLYMER INSTITUTE (NL) 2011-12-22 WO disclosed
US-4275250-A CHEMICAL INTERMEDIATES FOR VINYLCYCLOPROPANE CARBOXYLIC ACID ESTERS OF HALOGENATED BENZYL ALCOHOL WHICH ARE ARTHROPODICIDES BAYER AKTIENGESELLSCHAFT (DE) 1981-06-23 US disclosed
US-4183950-A Combating arthropods with 2,2-dimethyl-3-vinyl-cyclopropane carboxylic acid esters of halogenated benzyl alcohols BAYER AKTIENGESELLSCHAFT (DE) 1980-01-15 US disclosed