Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | MAPT | P10636 | 4/20 | 0.43 |
| ▸ | HPGD | P15428 | 7/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | KLK7 | P49862 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CASP1 | P29466 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.40 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4349007 | 0.86 | KMT2A (0.41) | TDP1GAAALDH1A1MAPTHPGD | |
| SCHEMBL4347126 | 0.85 | TDP1 (0.53) | TDP1GAAALDH1A1MAPTHPGD | |
| SCHEMBL4347278 | 0.82 | HPGD (0.59) | GAAALDH1A1MAPTHPGDRAB9A | |
| SCHEMBL4349456 | 0.81 | HPGD (0.40) | GAAALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL4353500 | 0.78 | ATM (0.44) | GAAALDH1A1MAPTHPGDKMT2A | |
| SCHEMBL4342450 | 0.78 | KDM4E (0.48) | GAAALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL4351639 | 0.71 | HPGD (0.59) | GAAALDH1A1MAPTHPGDKDM4E | |
| SCHEMBL4353434 | 0.71 | HPGD (0.61) | GAAALDH1A1HPGDKMT2AHSD17B10 | |
| SCHEMBL4347243 | 0.71 | MAPT (0.42) | TDP1GAAALDH1A1MAPTHPGD | |
| SCHEMBL16003043 | 0.71 | HPGD (0.54) | TDP1GAAALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2088149-A1 | PHARMACOLOGICALLY ACTIVE N,N'-SUBSTITUTED 3,7-DIAZABICYCLO Ý3.3.1¨NONANES, PHARMACEUTICAL COMPOSITIONS BASED THEREON AND A METHOD FOR THE USE THEREOF | Institute of Physiologically active compunds of the Russian Academy of Sciences (IPAC RAN) (RU) | 2009-08-12 | — | — | EP | claimed |
| EP-2088149-A1 | PHARMACOLOGICALLY ACTIVE N,N'-SUBSTITUTED 3,7-DIAZABICYCLO Ý3.3.1¨NONANES, PHARMACEUTICAL COMPOSITIONS BASED THEREON AND A METHOD FOR THE USE THEREOF | Institute of Physiologically active compunds of the Russian Academy of Sciences (IPAC RAN) (RU) | 2009-08-12 | — | — | EP | disclosed |