Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 6/20 | 0.53 |
| ▸ | PDE4A | P27815 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.46 |
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | RORC | P51449 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.39 |
| ▸ | CDK2 | P24941 | 2/20 | 0.39 |
| ▸ | CCNA1 | P78396 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PARP1 | P09874 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15444711 | 0.87 | HTR3A (0.56) | HTR3APDE4AKDM4EKCNH2RORC | |
| SCHEMBL4060213 | 0.87 | HTR3A (0.54) | HTR3APDE4AKDM4EKCNH2RORC | |
| SCHEMBL4368383 | 0.85 | PDE4A (0.47) | HTR3APDE4AKDM4EMAP3K14KCNH2 | |
| SCHEMBL4058462 | 0.83 | HTR3A (0.54) | HTR3APDE4AKCNH2 | |
| Hydrochloric Acid SCHEMBL4063231 | 0.82 | HTR3A (0.53) | HTR3APDE4AKCNH2 | |
| SCHEMBL15441066 | 0.82 | HTR3A (0.55) | HTR3APDE4AKDM4EKCNH2RORC | |
| SCHEMBL4062645 | 0.82 | HTR3A (0.55) | HTR3APDE4AKDM4EKCNH2TSHR | |
| SCHEMBL7169948 | 0.81 | PDE4A (0.54) | HTR3APDE4AKDM4EKCNH2RORC | |
| SCHEMBL21265544 | 0.80 | PDE4A (0.46) | HTR3APDE4AKDM4EMAP3K14KCNH2 | |
| SCHEMBL30647398 | 0.80 | PDE4A (0.46) | HTR3APDE4AKDM4EMAP3K14KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009108551-A2 | HETEROARYL AMIDE ANALOGUES | H. LUNDBECK A/S (DK) | 2009-09-03 | — | — | WO | disclosed |