Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.41 |
| ▸ | ADH1B | P00325 | 1/20 | 0.36 |
| ▸ | ADH1C | P00326 | 1/20 | 0.36 |
| ▸ | ADH1A | P07327 | 1/20 | 0.36 |
| ▸ | ADH4 | P08319 | 1/20 | 0.36 |
| ▸ | ADH7 | P40394 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL866722 | 1.00 | CYP1A2 (0.50) | CYP1A2SIGMAR1ADH1BADH1CADH1A | |
| SCHEMBL867198 | 1.00 | CYP1A2 (0.50) | CYP1A2SIGMAR1ADH1BADH1CADH1A | |
| SCHEMBL867289 | 1.00 | CYP1A2 (0.50) | CYP1A2SIGMAR1ADH1BADH1CADH1A | |
| SCHEMBL867017 | 1.00 | CYP1A2 (0.50) | CYP1A2SIGMAR1ADH1BADH1CADH1A | |
| SCHEMBL497975 | 0.97 | — | — | |
| SCHEMBL868345 | 0.92 | — | — | |
| SCHEMBL867301 | 0.85 | — | — | |
| SCHEMBL5148005 | 0.84 | CYP1A2 (0.58) | CYP1A2SIGMAR1EPHX1 | |
| SCHEMBL7031133 | 0.82 | CYP1A2 (0.44) | CYP1A2SIGMAR1ADH1BADH1CADH1A | |
| SCHEMBL9719593 | 0.82 | CYP1A2 (0.44) | CYP1A2SIGMAR1ADH1BADH1CADH1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114656788-A | Cyclic imide resin composition, prepreg, copper-clad laminate, and printed circuit board | 信越化学工业株式会社 | 2022-06-24 | — | — | CN | disclosed |
| CN-108137537-B | Imino compounds having 2-chloropyrimidin-5-yl substituents as pest control agents | 巴斯夫欧洲公司 | 2021-07-23 | — | — | CN | disclosed |
| EP-2237774-B1 | THE USE OF 6-HALOGENO-(1,2,4)-TRIAZOLO-(1,5-a)-PYRIMIDINE COMPOUNDS FOR COMBATING PESTS IN AND ON ANIMALS | MERIAL LTD (US) | 2016-06-22 | — | — | EP | disclosed |
| EP-1662877-B1 | 6-HALOGENO-[1,2,4]TRIAZOLO[1,5-A]PYRIMIDINES FOR COMBATING ANIMAL PESTS | MERIAL LTD (US) | 2014-12-17 | — | — | EP | disclosed |
| US-8664235-B2 | 6-Halogeno-[1,2,4]triazolo[1,5-a]pyrimidines for combating animal pests | MERIAL LIMITED (US) | 2014-03-04 | — | — | US | disclosed |
| US-8492468-B2 | Polypropylene resin composition | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2013-07-23 | — | — | US | disclosed |
| EP-2595984-A1 | MICROBICIDES | Syngenta Participations AG (CH) | 2013-05-29 | — | — | EP | disclosed |
| EP-2595985-A1 | ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES | Syngenta Participations AG (CH) | 2013-05-29 | — | — | EP | disclosed |
| US-20120108422-A1 | Antifungal 1,2,4-triazolyl Derivatives | BASF SE (DE) | 2012-05-03 | — | — | US | disclosed |
| EP-2443109-A1 | TRIAZOLE COMPOUNDS CARRYING A SULFUR SUBSTITUENT | BASF SE (DE) | 2012-04-25 | — | — | EP | disclosed |
| EP-0271750-B1 | FUNGICIDAL CYCLOHEXYL AMINES | BASF Aktiengesellschaft (DE) | 1990-10-31 | — | — | EP | disclosed |
| US-4939171-A | Alkyl and alkenyl aryl ether derivatives; cosmetics | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 1990-07-03 | — | — | US | disclosed |
| EP-0315913-A1 | Antiseborrhoic topical compositions | Henkel Kommanditgesellschaft auf Aktien (DE) | 1989-05-17 | — | — | EP | disclosed |
| EP-0271750-A1 | Fungicidal cyclohexyl amines | BASF Aktiengesellschaft (DE) | 1988-06-22 | — | — | EP | disclosed |
| US-4324788-A | HYPOTENSIVE AGENTS | I.S.F. S.P.A. (IT) | 1982-04-13 | — | — | US | disclosed |
| US-4198429-A | BRONCHOSPASMOLYTIC | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-04-15 | — | — | US | disclosed |
| US-4104402-A | BRONCHODILATORS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1978-08-01 | — | — | US | disclosed |
| US-4035512-A | Aminotetralols | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1977-07-12 | — | — | US | disclosed |
| US-4010202-A | TREATMENT OF ASTHMA AND ARRHYTHMIA | TAKEDA CHEMICAL INDUSTRIES, LTD. (JA) | 1977-03-01 | — | — | US | disclosed |
| US-3994974-A | BRONCHODILATORS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JA) | 1976-11-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120108422-A1 | Antifungal 1,2,4-triazolyl Derivatives | ERG28, CYP51A1, DPM1 | CYP1A2 26/4885SIGMAR1 3126/4885ADH1B 3813/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.