SCHEMBL4351183

SCHEMBL4351183

CC(=O)OCCc1ccccc1.CC(=O)OCCc1ccccc1

nearest known ligand 0.64

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.64
HCAR2 Q8TDS4 1/20 0.58
TDP1 Q9NUW8 2/20 0.57
ESR1 P03372 1/20 0.56
ESR2 Q92731 1/20 0.56
NPC1 O15118 2/20 0.54
RAB9A P51151 2/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
AKR1B10 O60218 2/20 0.54
AKR1B1 P15121 2/20 0.54
TP53 P04637 1/20 0.54
GLA P06280 1/20 0.54
CYP3A4 P08684 1/20 0.54
HPGD P15428 1/20 0.54
TSHR P16473 1/20 0.54
MAPK1 P28482 1/20 0.54
SMN1; SMN2 Q16637 1/20 0.54
HIF1A Q16665 1/20 0.54
HSD17B10 Q99714 1/20 0.54
LMNA P02545 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL111422 1.00 ALDH1A1 (0.64) ALDH1A1HCAR2TDP1ESR1ESR2
Benzene SCHEMBL19304565 1.00 ALDH1A1 (0.64) ALDH1A1HCAR2TDP1ESR1ESR2
Acetic Acid SCHEMBL28067643 0.98 ALDH1A1 (0.62) ALDH1A1HCAR2TDP1ESR1ESR2
Hydrochloric Acid SCHEMBL27545520 0.98 ALDH1A1 (0.62) ALDH1A1HCAR2TDP1ESR1ESR2
SCHEMBL27897041 0.98 ALDH1A1 (0.62) ALDH1A1HCAR2TDP1ESR1ESR2
Acetic Acid SCHEMBL19951529 0.98 ALDH1A1 (0.62) ALDH1A1HCAR2TDP1ESR1ESR2
SCHEMBL28201295 0.98 ALDH1A1 (0.62) ALDH1A1HCAR2TDP1ESR1ESR2
Ethyne SCHEMBL27579020 0.96 ALDH1A1 (0.60) ALDH1A1HCAR2TDP1ESR1ESR2
Alcohol SCHEMBL4648875 0.94 ALDH1A1 (0.58) ALDH1A1HCAR2TDP1ESR1ESR2
Trimethylammonium SCHEMBL9482623 0.94 ALDH1A1 (0.58) ALDH1A1HCAR2TDP1ESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2124743-A1 MEDICATION ADHERENCE MONITORING SYSTEM UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2009-12-02 EP disclosed
WO-2008103924-A2 MEDICATION ADHERENCE MONITORING SYSTEM UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) 2008-08-28 WO disclosed