SCHEMBL4351575

SCHEMBL4351575

CCC[Si](C)(O)NCCN

nearest known ligand 0.30

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
CYP2C9 P11712 1/20 0.30
HPGD P15428 1/20 0.30
ALOX15 P16050 1/20 0.30
CYP2C19 P33261 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL530339 0.73
Potassium Ion SCHEMBL8214633 0.71
SCHEMBL2547705 0.70 CA12 (0.36) ALDH1A1CYP2C9ALOX15CYP2C19
SCHEMBL238151 0.70
SCHEMBL758253 0.68
SCHEMBL28345527 0.68
SCHEMBL29078704 0.67 CA12 (0.50) ALDH1A1CYP2C9ALOX15CYP2C19HSD17B10
SCHEMBL2436759 0.67
SCHEMBL9541634 0.66
SCHEMBL17627177 0.65

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20150000562-A1 HYDROPHOBING AGENT FOR COATINGS WACKER CHEMIE AG (DE) 2015-01-01 US disclosed
US-20090260769-A1 METHOD FOR TREATING CELLULOSE-CONTAINING FIBERS OR PLANAR STRUCTURES CONTAINING CELLULOSE-CONTAINING FIBERS WACKER CHEMIE AG (DE) 2009-10-22 US disclosed
US-5494949-A SILANIZING INORGANIC OXIDES FOR COVALENT BONDING TO POLYESTER; FILLERS, REDUCTION OF VOIDS IN FILMS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1996-02-27 US disclosed