SCHEMBL4351657

SCHEMBL4351657

CO[SiH](OC)C(C)CCSCCC(C)[SiH](OC)OC

nearest known ligand 0.36

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
ROCK2 O75116 1/20 0.36
BHMT Q93088 1/20 0.31
BHMT2 Q9H2M3 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL551776 0.85
SCHEMBL15239908 0.81
SCHEMBL543624 0.81
SCHEMBL28463100 0.78
SCHEMBL2566480 0.76
SCHEMBL4354375 0.76 ROCK2 (0.34) ROCK2
SCHEMBL28348358 0.74
SCHEMBL28458913 0.74
SCHEMBL28460091 0.74
SCHEMBL1608791 0.74 TSHR (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090277559-A1 METHOD FOR VULCANIZATION-ADHERING RUBBER COMPOSITION TO ADHERENT OF BRASS OR PLATED WITH BRASS, REINFORCING MEMBER FOR RUBBER ARTICLE, RUBBER-REINFORCING MEMBER COMPOSITE AND PNEUMATIC TIRE BRIDGESTONE CORPORATION (JP) 2009-11-12 US disclosed