Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 10/20 | 0.61 |
| ▸ | F10 | P00742 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | BMP1 | P13497 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6186875 | 0.90 | BDKRB1 (0.57) | BDKRB1TDP1TP53BCHEACHE | |
| SCHEMBL4027525 | 0.89 | BDKRB1 (0.62) | BDKRB1F10TDP1TP53BCHE | |
| SCHEMBL4040827 | 0.84 | BDKRB1 (0.66) | BDKRB1BCHEACHE | |
| SCHEMBL4027742 | 0.82 | BDKRB1 (0.59) | BDKRB1TDP1TP53BCHEACHE | |
| SCHEMBL4031279 | 0.78 | BDKRB1 (0.97) | BDKRB1 | |
| SCHEMBL4030655 | 0.77 | BDKRB1 (0.72) | BDKRB1TDP1BCHEACHE | |
| SCHEMBL5118277 | 0.76 | BDKRB1 (0.66) | BDKRB1TP53LMNA | |
| SCHEMBL4036657 | 0.76 | BDKRB1 (1.00) | BDKRB1 | |
| SCHEMBL6767059 | 0.75 | BDKRB1 (0.61) | BDKRB1F10BMP1TP53MEN1 | |
| SCHEMBL6767060 | 0.75 | BDKRB1 (0.61) | BDKRB1F10BMP1TP53MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1521744-B1 | ARYLSULPHONAMIDE DERIVATIVES AND USE THEREOF AS B1 BRADYKININ RECEPTOR ANTAGONISTS | FOURNIER LAB SA (FR) | 2009-04-01 | — | — | EP | disclosed |