Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 9/20 | 0.57 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4351895 | 0.90 | BDKRB1 (0.61) | BDKRB1TDP1TP53BCHEACHE | |
| SCHEMBL4027742 | 0.86 | BDKRB1 (0.59) | BDKRB1TDP1TP53BCHEACHE | |
| SCHEMBL4027525 | 0.86 | BDKRB1 (0.62) | BDKRB1TDP1TP53BCHEACHE | |
| SCHEMBL6186876 | 0.85 | BDKRB1 (0.42) | BDKRB1TDP1TP53HPGDNPC1 | |
| SCHEMBL4027737 | 0.85 | BDKRB1 (0.42) | BDKRB1TDP1TP53HPGDNPC1 | |
| SCHEMBL4040827 | 0.80 | BDKRB1 (0.66) | BDKRB1BCHEACHERAB9A | |
| SCHEMBL6982375 | 0.77 | BDKRB1 (0.58) | BDKRB1TP53MEN1KMT2ALMNA | |
| SCHEMBL4031279 | 0.75 | BDKRB1 (0.97) | BDKRB1 | |
| SCHEMBL4030655 | 0.74 | BDKRB1 (0.72) | BDKRB1TDP1BCHEACHE | |
| SCHEMBL5118277 | 0.73 | BDKRB1 (0.66) | BDKRB1TP53LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1521744-A1 | ARYLSULPHONAMIDE DERIVATIVES AND USE THEREOF AS B1 BRADYKININ RECEPTOR ANTAGONISTS | LABORATOIRES FOURNIER S.A. (FR) | 2005-04-13 | — | — | EP | disclosed |
| WO-2003106428-A1 | NOVEL ARYLSULPHONAMIDE DERIVATIVES AND USE THEREOF AS THERAPEUTIC AGENTS | LABORATOIRES FOURNIER SA (FR) | 2003-12-24 | — | — | WO | disclosed |