Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AHR | P35869 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | EDNRB | P24530 | 1/20 | 0.35 |
| ▸ | EDNRA | P25101 | 1/20 | 0.35 |
| ▸ | GCGR | P47871 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.34 |
| ▸ | SHMT1 | P34896 | 1/20 | 0.33 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.33 |
| ▸ | MARS1 | P56192 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL433433 | 0.86 | GRM2 (0.36) | AHRHSD11B1 | |
| SCHEMBL17514779 | 0.86 | NISCH (0.38) | AHRTP53RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL432623 | 0.81 | AHR (0.52) | AHRTP53RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL15637453 | 0.80 | CYP2A6 (0.47) | TP53RAB9ANPC1SMN1; SMN2HSD11B1 | |
| SCHEMBL5182079 | 0.79 | AHR (0.40) | AHRTP53ALDH1A1TSHRHSD17B10 | |
| SCHEMBL15637337 | 0.79 | AHR (0.59) | AHRTP53RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL15636311 | 0.79 | AHR (0.48) | AHRTP53RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL15637460 | 0.78 | AHR (0.44) | AHRTP53RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL433164 | 0.77 | ALOX5 (0.42) | AHRTP53RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL434492 | 0.75 | AHR (0.57) | AHRTP53RAB9ANPC1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2595984-A1 | MICROBICIDES | Syngenta Participations AG (CH) | 2013-05-29 | — | — | EP | disclosed |
| EP-2595985-A1 | ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES | Syngenta Participations AG (CH) | 2013-05-29 | — | — | EP | disclosed |
| WO-2012010568-A1 | MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-01-26 | — | — | WO | disclosed |
| WO-2012010567-A1 | ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-01-26 | — | — | WO | disclosed |