Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | ATM | Q13315 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | FABP4 | P15090 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | MITF | O75030 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.42 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.42 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28024648 | 0.85 | AKR1C3 (0.49) | KMT2AKDM4EFABP4ALDH1A1MAPT | |
| SCHEMBL20923997 | 0.83 | KMT2A (0.55) | KMT2AALDH1A1MAPTMITFLMNA | |
| SCHEMBL10596904 | 0.82 | KDM4E (0.50) | KMT2AATMKDM4EFABP4ALDH1A1 | |
| SCHEMBL27405880 | 0.80 | POLB (0.41) | KMT2AKDM4EALDH1A1MAPTMITF | |
| SCHEMBL2174829 | 0.79 | NR4A2 (0.65) | KMT2AKDM4EALDH1A1MAPTMITF | |
| SCHEMBL784673 | 0.79 | KDM4E (0.44) | KMT2AATMKDM4EFABP4ALDH1A1 | |
| SCHEMBL21725009 | 0.79 | KMT2A (0.49) | KMT2AATMKDM4EFABP4ALDH1A1 | |
| SCHEMBL27873322 | 0.79 | NR4A2 (0.69) | KMT2AKDM4EALDH1A1MAPTLMNA | |
| SCHEMBL27387445 | 0.78 | KMT2A (0.48) | KMT2AATMKDM4EFABP4ALDH1A1 | |
| SCHEMBL579555 | 0.77 | NR4A2 (0.65) | KDM4EFABP4ALDH1A1LMNANR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109665985-A | Polysubstituted Benzazole compounds and its application | 中国科学院广州生物医药与健康研究院 | 2019-04-23 | — | — | CN | disclosed |
| WO-2009108551-A2 | HETEROARYL AMIDE ANALOGUES | H. LUNDBECK A/S (DK) | 2009-09-03 | — | — | WO | disclosed |