Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 6/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.63 |
| ▸ | ABL1 | P00519 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.63 |
| ▸ | IDE | P14735 | 1/20 | 0.63 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.63 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.63 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.63 |
| ▸ | CA12 | O43570 | 8/20 | 0.57 |
| ▸ | CA1 | P00915 | 8/20 | 0.57 |
| ▸ | CA2 | P00918 | 8/20 | 0.57 |
| ▸ | CA9 | Q16790 | 8/20 | 0.57 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.56 |
| ▸ | HLCS | P50747 | 4/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21488913 | 1.00 | TDP1 (0.65) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL13585655 | 1.00 | TDP1 (0.65) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL21488912 | 1.00 | TDP1 (0.65) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL27996441 | 1.00 | TDP1 (0.65) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL28161084 | 0.99 | TDP1 (0.64) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL23124066 | 0.84 | TDP1 (0.74) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL29556007 | 0.84 | TDP1 (0.74) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL7157942 | 0.84 | TDP1 (0.77) | TDP1MEN1ABL1LMNAPKM | |
| SCHEMBL4829292 | 0.83 | TDP1 (0.53) | TDP1MEN1ABL1LMNAPKM | |
| Biotin SCHEMBL446893 | 0.83 | TDP1 (0.79) | TDP1MEN1ABL1LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 31 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105198901-B | The improved method that a kind of de- benzyl synthesizes d biotins | 浙江医药股份有限公司新昌制药厂 | 2017-08-15 | — | — | CN | claimed |
| CN-104710437-B | Improved method for preparing d-biotin from bisbenzyl biotin by debenzylation | 富阳科兴生物化工有限公司 | 2017-01-25 | — | — | CN | claimed |
| JP-55104286-A | — | — | None | — | — | JP | disclosed |
| CN-121873095-A | Single benzyl biotin product, preparation method and application of single benzyl biotin | 江西天新药业股份有限公司 | 2026-04-17 | — | — | CN | disclosed |
| CN-121873095-A | Single benzyl biotin product, preparation method and application of single benzyl biotin | 江西天新药业股份有限公司 | 2026-04-17 | — | — | CN | disclosed |
| CN-117800985-A | Preparation method of 1'N-benzyl biotin | 浙江圣达生物药业股份有限公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-114790211-B | Biotin and preparation method thereof | 浙江花园营养科技有限公司 | 2023-11-17 | — | — | CN | disclosed |
| CN-114790211-A | Biotin and preparation method thereof | 浙江花园营养科技有限公司 | 2022-07-26 | — | — | CN | disclosed |
| CN-112390815-B | Preparation method for preparing d-biotin by removing N-benzyl from Lewis acid | 浙江医药股份有限公司新昌制药厂 | 2022-07-26 | — | — | CN | disclosed |
| WO-2022088291-A1 | GROUP TRANSFER METHOD FOR SELECTIVE MODIFICATION OF TARGET PROTEIN AND USE THEREOF | 北京大学深圳研究生院 | 2022-05-05 | — | — | WO | disclosed |
| CN-112390815-A | Preparation method for preparing d-biotin by removing N-benzyl group with Lewis acid | 浙江医药股份有限公司新昌制药厂 | 2021-02-23 | — | — | CN | disclosed |
| CN-101215291-B | Synthesis method of (+)-biotin and its derivatives | UNIV FUDAN | 2010-12-29 | — | — | CN | disclosed |
| US-7635571-B2 | photosenstizer generates singlet oxygen which oxidatively cleaves the linker to form a product which can be detected in a sandwich detection assay; kits | SIEMENS HEALTHCARE DIAGNOSTICS PRODUCTS GMBH (DE) | 2009-12-22 | — | — | US | disclosed |
| CN-101215292-A | Synthesis method of dibenzylbiotin and its derivatives | UNIV FUDAN (CN) | 2008-07-09 | — | — | CN | disclosed |
| CN-101215291-A | Synthesis method of (+)-biotin and its derivatives | UNIV FUDAN (CN) | 2008-07-09 | — | — | CN | disclosed |
| US-20040175696-A1 | Amplified luminescent homogeneous immunoassay | SIEMENS HEALTHCARE DIAGNOSTICS PRODUCTS GMBH (DE) | 2004-09-09 | — | — | US | disclosed |
| US-6555528-B2 | Protease inhibitor | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE | 2003-04-29 | — | — | US | disclosed |
| US-20010016343-A1 | Derivatized biotin compounds and methods | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2001-08-23 | — | — | US | disclosed |
| US-6242610-B1 | REACTING PHENYLMETHYL 5-(6,8-DIAZA-6-(2-X-ACETYL)-7-OXO-3-THIABICYCLO(3.3.0)OCT-2-YL)PENTANOATE WITH HIV PROTEASE TO REDUCE THE ACTIVITY OF THE PROTEASE | BOARD OF SUPERVISORS OF LOUISIANA STATE UNIVERSITY AND AGRICULTURAL AND MECHANICAL COLLEGE | 2001-06-05 | — | — | US | disclosed |
| JP-S55104286-A | PREPARATION OF THIENOIMIDAZOLINE COMPOUND | SUMITOMO CHEM CO LTD | 1980-08-09 | — | — | JP | disclosed |