Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 5/20 | 0.79 |
| ▸ | MEN1 | O00255 | 1/20 | 0.79 |
| ▸ | ABL1 | P00519 | 1/20 | 0.79 |
| ▸ | LMNA | P02545 | 1/20 | 0.79 |
| ▸ | PKM | P14618 | 1/20 | 0.79 |
| ▸ | IDE | P14735 | 1/20 | 0.79 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.79 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.79 |
| ▸ | RIN1 | Q13671 | 1/20 | 0.79 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.79 |
| ▸ | CA12 | O43570 | 10/20 | 0.64 |
| ▸ | CA1 | P00915 | 10/20 | 0.64 |
| ▸ | CA2 | P00918 | 10/20 | 0.64 |
| ▸ | CA9 | Q16790 | 10/20 | 0.64 |
| ▸ | HLCS | P50747 | 3/20 | 0.56 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Biotin SCHEMBL16147350 | 0.91 | TDP1 (0.76) | TDP1MEN1ABL1LMNAPKM | |
| Biotin SCHEMBL16148338 | 0.91 | TDP1 (0.76) | TDP1MEN1ABL1LMNAPKM | |
| Biotin SCHEMBL18993019 | 0.91 | TDP1 (0.83) | TDP1MEN1ABL1LMNAPKM | |
| Biotin SCHEMBL23124079 | 0.89 | TDP1 (0.81) | TDP1MEN1ABL1LMNAPKM | |
| Biotin SCHEMBL723192 | 0.89 | TDP1 (0.90) | TDP1MEN1ABL1LMNAPKM | |
| Biotin SCHEMBL21981206 | 0.89 | TDP1 (1.00) | TDP1MEN1ABL1LMNAPKM | |
| Biotin SCHEMBL22943835 | 0.89 | TDP1 (1.00) | TDP1MEN1ABL1LMNAPKM | |
| Biotin SCHEMBL20547409 | 0.89 | TDP1 (1.00) | TDP1MEN1ABL1LMNAPKM | |
| Biotin SCHEMBL38817 | 0.89 | TDP1 (1.00) | TDP1MEN1ABL1LMNAPKM | |
| Biotin SCHEMBL10047687 | 0.89 | TDP1 (1.00) | TDP1MEN1ABL1LMNAPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118063486-A | Preparation method of (3 aS, 4S, 6 aR) -dibenzyl biotin | 浙江医药股份有限公司 | 2024-05-24 | — | — | CN | claimed |
| CN-115532290-B | Specific crystal face selective hydrogenation catalyst and preparation method and application thereof | 浙江昌海制药有限公司 | 2024-04-30 | — | — | CN | claimed |
| CN-117800985-A | Preparation method of 1'N-benzyl biotin | 浙江圣达生物药业股份有限公司 | 2024-04-02 | — | — | CN | claimed |
| CN-115532290-A | Specific crystal face selective hydrogenation catalyst and preparation method and application thereof | 浙江昌海制药有限公司 | 2022-12-30 | — | — | CN | claimed |
| CN-112390815-B | Preparation method for preparing d-biotin by removing N-benzyl from Lewis acid | 浙江医药股份有限公司新昌制药厂 | 2022-07-26 | — | — | CN | claimed |
| CN-112457327-A | Preparation method of D-biotin | 安徽泰格维生素实业有限公司 | 2021-03-09 | — | — | CN | claimed |
| CN-112390815-A | Preparation method for preparing d-biotin by removing N-benzyl group with Lewis acid | 浙江医药股份有限公司新昌制药厂 | 2021-02-23 | — | — | CN | claimed |
| CN-102268007-B | The preparation method of dibenzyl biotin derivative | ZHEJIANG XINHECHENG CO., LTD. (CN) | 2015-11-25 | — | — | CN | claimed |
| CN-101328185-B | Method for synthesizing biotin from 1,3-dibenzyl-4-alkoxy biotin intermediate | ZHEJIANG MED XINCHANG PHARM | 2013-12-11 | — | — | CN | claimed |
| CN-114480525-B | Production method for improving yield of D-biotin | 浙江圣达生物药业股份有限公司 | 2024-06-07 | — | — | CN | disclosed |
| CN-118063486-A | Preparation method of (3 aS, 4S, 6 aR) -dibenzyl biotin | 浙江医药股份有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-118063486-A | Preparation method of (3 aS, 4S, 6 aR) -dibenzyl biotin | 浙江医药股份有限公司 | 2024-05-24 | — | — | CN | disclosed |
| CN-115532290-B | Specific crystal face selective hydrogenation catalyst and preparation method and application thereof | 浙江昌海制药有限公司 | 2024-04-30 | — | — | CN | disclosed |
| CN-117800985-A | Preparation method of 1'N-benzyl biotin | 浙江圣达生物药业股份有限公司 | 2024-04-02 | — | — | CN | disclosed |
| EP-0971931-B1 | METHOD FOR DEBENZYLATION OF DIBENZYL BIOTIN | MERCK PATENT GMBH (DE) | 2003-02-19 | — | — | EP | disclosed |
| CN-1101820-C | Method for debenzylation of dibenzyl biotin | MERCK PATENT GMBH (DE) | 2003-02-19 | — | — | CN | disclosed |
| CN-1251106-A | Method for debenzylation of dibenzyl biotin | MERCK PATENT GMBH (DE) | 2000-04-19 | — | — | CN | disclosed |
| CN-1251106-A | Method for debenzylation of dibenzyl biotin | MERCK PATENT GMBH (DE) | 2000-04-19 | — | — | CN | disclosed |
| EP-0971931-A1 | METHOD FOR DEBENZYLATION OF DIBENZYL BIOTIN | MERCK PATENT GmbH (DE) | 2000-01-19 | — | — | EP | disclosed |
| WO-1998043979-A1 | METHOD FOR DEBENZYLATION OF DIBENZYL BIOTIN | MERCK PATENT GMBH (DE) | 1998-10-08 | — | — | WO | disclosed |