Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.41 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.41 |
| ▸ | AHR | P35869 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.38 |
| ▸ | ALDH1A2 | O94788 | 1/20 | 0.37 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.35 |
| ▸ | RELA | Q04206 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3978906 | 0.86 | CYP2A6 (0.50) | CYP1A2PTGS2PTGS1ALDH1A2ALDH1A3 | |
| SCHEMBL4281566 | 0.84 | CYP2A6 (0.48) | CYP1A2PTGS2ALDH1A2ALDH1A3CYP2A6 | |
| SCHEMBL5584101 | 0.83 | IDO1 (0.32) | CYP2A6 | |
| SCHEMBL2430751 | 0.83 | PTGS2 (0.39) | PTGS2PTGS1SLC6A4SLC6A3ALDH1A3 | |
| SCHEMBL4394322 | 0.83 | CYP2A6 (0.32) | CYP2A6 | |
| SCHEMBL6881481 | 0.83 | HPGD (0.36) | CYP2A6KDM4EALDH1A1NPC1RAB9A | |
| SCHEMBL4653269 | 0.83 | CYP1A2 (0.39) | CYP1A2PTGS2PTGS1AHRSLC6A4 | |
| SCHEMBL9667400 | 0.83 | MAPK1 (0.39) | CYP1A2SLC6A3CYP2A6LMNAKDM4E | |
| SCHEMBL11514621 | 0.83 | CYP3A4 (0.40) | PTGS2PTGS1CYP2A6ALDH1A1TP53 | |
| SCHEMBL11746658 | 0.81 | CYP1A2 (0.38) | CYP1A2PTGS2PTGS1AHRSLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4335142-A | MICROBIOCIDES | UNIROYAL, INC. (US) | 1982-06-15 | — | — | US | claimed |
| US-9307767-B2 | Herbicidally and insecticidally active thiazolopyridinones | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2016-04-12 | — | — | US | disclosed |
| EP-2831084-B1 | HERBICIDAL AND INSECTICIDAL THIAZOLOPYRIDINONES | BAYER IP GMBH (DE) | 2016-03-23 | — | — | EP | disclosed |
| WO-2015089349-A1 | INHIBITION OF ISOPRENOID BIOSYNTHETIC PATHWAYS TO TREAT NEUROINFLAMMATORY DISORDERS | TABACZYNSKI DAVID A (US) | 2015-06-18 | — | — | WO | disclosed |
| WO-2015084721-A1 | INHIBITION OF ISOPRENOID BIOSYNTHETIC PATHWAYS TO TREAT AUTOIMMUNE DISORDERS | TABACZYNSKI DAVID A (US) | 2015-06-11 | — | — | WO | disclosed |
| US-20150045217-A1 | Herbicidally and Insecticidally Active Thiazolopyridinones | BAYER CROPSCIENCE AKTIENGESELLSCHAFT (DE) | 2015-02-12 | — | — | US | disclosed |
| EP-2831084-A1 | HERBICIDALLY AND INSECTICIDALLY ACTIVE THIAZOLOPYRIDINONES | Bayer Intellectual Property GmbH (DE) | 2015-02-04 | — | — | EP | disclosed |
| WO-2013144096-A1 | HERBICIDALLY AND INSECTICIDALLY ACTIVE THIAZOLOPYRIDINONES | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2013-10-03 | — | — | WO | disclosed |
| EP-2595985-A1 | ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES | Syngenta Participations AG (CH) | 2013-05-29 | — | — | EP | disclosed |
| EP-2595984-A1 | MICROBICIDES | Syngenta Participations AG (CH) | 2013-05-29 | — | — | EP | disclosed |
| WO-2012010568-A1 | MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-01-26 | — | — | WO | disclosed |
| WO-2012010567-A1 | ISOXAZOLE, ISOTHIAZOLE, FURANE AND THIOPHENE COMPOUNDS AS MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2012-01-26 | — | — | WO | disclosed |
| EP-2237669-A2 | CHEMICAL COMPOUNDS | Syngenta Limited (GB) | 2010-10-13 | — | — | EP | disclosed |
| WO-2009081112-A2 | CHEMICAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2009-07-02 | — | — | WO | disclosed |
| CN-1262679-A | IL-5 inhibiting 6-azauracil derivatives | JANSSEN PHARMACEUTICA NV (BE) | 2000-08-09 | — | — | CN | disclosed |
| US-4946493-A | FUNGICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1990-08-07 | — | — | US | disclosed |
| US-4845250-A | FUNGICIDES, PLANT GROWTH REGULATORS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-07-04 | — | — | US | disclosed |
| US-4820704-A | Pyridazinone derivatives and their use as fungicides | BASF AKTIENGESELLSCHAFT (DE) | 1989-04-11 | — | — | US | disclosed |
| US-4507140-A | GALLIUM ARSENIDE DOPED WITH GERMANIUM AND TELLURIUM | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-03-26 | — | — | US | disclosed |
| US-4501746-A | HERBICIDES; PLANT GROWTH REGULATORS | ELI LILLY AND COMPANY (US) | 1985-02-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150045217-A1 | Herbicidally and Insecticidally Active Thiazolopyridinones | CBR3, DDT, CBR1 | CYP1A2 121/4885PTGS2 1811/4885PTGS1 1080/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.