SCHEMBL4352680

SCHEMBL4352680

On1cncn1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2513229 0.62
SCHEMBL7268279 0.61 ALDH1A1 (0.43)
SCHEMBL24211656 0.61 ALDH1A1 (0.35)
SCHEMBL9697494 0.60
SCHEMBL12578966 0.58
SCHEMBL6959213 0.55
Dimethylamine SCHEMBL18492449 0.55
SCHEMBL21850758 0.55
SCHEMBL8512657 0.42 HSP90AA1 (0.36)
SCHEMBL27007968 0.42 HSP90AA1 (0.36)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 94 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250320340-A1 PROCESSES FOR PRODUCING FILLED POLYOL COMPOSITIONS COVESTRO LLC (US) 2025-10-16 US claimed
EP-4396254-A1 PROCESSES FOR PRODUCING FILLED POLYOL COMPOSITIONS Covestro LLC (US) 2024-07-10 EP claimed
EP-4396253-A1 FILLED POLYOL COMPOSITIONS THAT INCLUDE A TRIAZOLE Covestro LLC (US) 2024-07-10 EP claimed
US-20230083992-A1 FILLED POLYOL COMPOSITIONS THAT INCLUDE A TRIAZOLE COVESTRO LLC 2023-03-16 US claimed
WO-2023033997-A1 FILLED POLYOL COMPOSITIONS THAT INCLUDE A TRIAZOLE COVESTRO LLC (US) 2023-03-09 WO claimed
WO-2023033998-A1 PROCESSES FOR PRODUCING FILLED POLYOL COMPOSITIONS COVESTRO LLC (US) 2023-03-09 WO claimed
CN-114728918-A RIP1 inhibiting compounds and methods of making and using the same 里格尔药品股份有限公司 2022-07-08 CN claimed
EP-2490688-A1 COMBINATION CANCER THERAPY WITH HSP90 INHIBITORY COMPOUNDS Synta Pharmaceuticals Corp. (US) 2012-08-29 EP claimed
EP-1329160-A2 4-ACYLAMINOPYRAZOLE DERIVATIVES Sankyo Company, Limited (JP) 2003-07-23 EP claimed
EP-0421227-B1 1-Hydroxy-1,2,4-triazole derivatives and fungicides containing them and growth regulators BASF AG (DE) 1994-06-15 EP claimed
EP-0378082-B1 1-Hydroxy-1,2,4-triazoles BASF AG (DE) 1994-06-08 EP claimed
EP-0384365-B1 0-(1,2,4-Triazolyl-1)-0-phenyl acetals and fungicides containing them BASF AG (DE) 1993-12-08 EP claimed
EP-0385371-B1 1-HYDROXY-1,2,4-TRIAZOLE DERIVATIVES AND FUNGICIDES CONTAINING THEM BASF Aktiengesellschaft (DE) 1992-07-01 EP claimed
US-5049678-A Fungicides, growth regulators, biocides BASF AKTIENGESELLSCHAFT (DE) 1991-09-17 US claimed
EP-0421227-A2 1-Hydroxy-1,2,4-triazole derivatives and fungicides containing them and growth regulators BASF Aktiengesellschaft (DE) 1991-04-10 EP claimed
EP-0396078-A2 1-Hydroxy-azole derivatives and fungicides containing them BASF Aktiengesellschaft (DE) 1990-11-07 EP claimed
EP-0385371-A1 1-Hydroxy-1,2,4-triazole derivatives and fungicides containing them BASF Aktiengesellschaft (DE) 1990-09-05 EP claimed
EP-0378082-A1 1-Hydroxy-1,2,4-triazoles BASF Aktiengesellschaft (DE) 1990-07-18 EP claimed
JP-2233664-A None JP disclosed
US-4055572-A Process for the production of 3-hydroxy-1,2,4-triazole derivatives CIBA-GEIGY CORPORATION (US) 1977-10-25 US disclosed