Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Tyrosine. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 3/20 | 0.61 |
| ▸ | ITGA4 | P13612 | 7/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.45 |
| ▸ | ALPI | P09923 | 1/20 | 0.45 |
| ▸ | PKM | P14618 | 1/20 | 0.45 |
| ▸ | XIAP | P98170 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 2/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | USP2 | O75604 | 1/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.43 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tyrosine SCHEMBL4205059 | 1.00 | SLC7A5 (0.61) | SLC7A5ITGA4PTGS1ALPIPKM | |
| Tyrosine SCHEMBL5152642 | 1.00 | SLC7A5 (0.61) | SLC7A5ITGA4PTGS1ALPIPKM | |
| Tyrosine SCHEMBL4205061 | 1.00 | SLC7A5 (0.61) | SLC7A5ITGA4PTGS1ALPIPKM | |
| Tyrosine SCHEMBL10757101 | 0.96 | SLC7A5 (0.57) | SLC7A5ITGA4PTGS1ALPIPKM | |
| Tyrosine SCHEMBL6665573 | 0.95 | SLC7A5 (0.56) | SLC7A5ITGA4PTGS1ALPIPKM | |
| Tyrosine SCHEMBL22290100 | 0.95 | SLC7A5 (0.56) | SLC7A5ITGA4PTGS1ALPIPKM | |
| Tyrosine SCHEMBL17728297 | 0.95 | SLC7A5 (0.56) | SLC7A5ITGA4PTGS1ALPIPKM | |
| Tyrosine SCHEMBL17728298 | 0.95 | SLC7A5 (0.56) | SLC7A5ITGA4PTGS1ALPIPKM | |
| Tyrosine SCHEMBL1675510 | 0.95 | SLC7A5 (0.56) | SLC7A5ITGA4PTGS1ALPIPKM | |
| Tyrosine SCHEMBL3100805 | 0.95 | SLC7A5 (0.56) | SLC7A5ITGA4PTGS1ALPIPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2958971-B1 | MULTI COMPONENT ADHESIVE FOR THE PREPARATION OF ADHESIVE HYDROGELS | FRAUNHOFER GES FORSCHUNG (DE) | 2018-07-11 | — | — | EP | claimed |
| US-20160130484-A1 | MULTI-COMPONENT ADHESIVE FOR PRODUCING AN ADHESIVE HYDROGEL | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2016-05-12 | — | — | US | claimed |
| US-20240093218-A1 | NUCLEIC ACID CONSTRUCTS, PLANTS WITH INCREASED TUBER YIELD, AND METHODS FOR INCREASING TUBER YIELD IN A PLANT | NATIONAL SCIENCE FOUNDATION | 2024-03-21 | — | — | US | disclosed |
| US-11795468-B2 | Nucleic acid constructs, plants with increased tuber yield, and methods for increasing tuber yield in a plant | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2023-10-24 | — | — | US | disclosed |
| US-20190218565-A1 | NUCLEIC ACID CONSTRUCTS, PLANTS WITH INCREASED TUBER YIELD, AND METHODS FOR INCREASING TUBER YIELD IN A PLANT | NATIONAL SCIENCE FOUNDATION | 2019-07-18 | — | — | US | disclosed |
| US-20160130484-A1 | MULTI-COMPONENT ADHESIVE FOR PRODUCING AN ADHESIVE HYDROGEL | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. (DE) | 2016-05-12 | — | — | US | disclosed |
| US-7579150-B1 | screening a biomolecule such as protein, polypeptide, or ribonucleoprotein, for its ability to assist in mediating long-distance movement of a mobile RNA through phloem tissue of a plant; for enhancing growth in a plant | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2009-08-25 | — | — | US | disclosed |
| US-20080184396-A1 | POTATO TRANSCRIPTION FACTORS, METHODS OF USE THEREOF, AND A METHOD FOR ENHANCING TUBER DEVELOPMENT | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2008-07-31 | — | — | US | disclosed |
| US-7265263-B1 | Potato transcription factors, methods of use thereof, and a method for enhancing tuber development | IOWA STATE UNIVERSITY RESEARCH FOUNDATION, INC. (US) | 2007-09-04 | — | — | US | disclosed |