Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 5/20 | 0.64 |
| ▸ | CES2 | O00748 | 4/20 | 0.64 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | DAO | P14920 | 1/20 | 0.52 |
| ▸ | NAPRT | Q6XQN6 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | CA2 | P00918 | 2/20 | 0.48 |
| ▸ | CA4 | P22748 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | PARP1 | P09874 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | RECQL | P46063 | 1/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.48 |
| ▸ | CA12 | O43570 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4781088 | 0.83 | CES1 (0.56) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL3281774 | 0.82 | CES2 (0.52) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL5956858 | 0.81 | CES2 (0.68) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL177165 | 0.79 | TSHR (0.56) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL15180810 | 0.78 | CES2 (1.00) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL11125364 | 0.78 | CES1 (0.64) | CES1CES2TSHRALDH1A1DAO | |
| Acetophenone SCHEMBL5526660 | 0.78 | MAPT (0.65) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL180411 | 0.78 | CES2 (1.00) | CES1CES2TSHRALDH1A1DAO | |
| SCHEMBL12457714 | 0.78 | CES1 (0.64) | CES1CES2TSHRALDH1A1DAO | |
| Benzil SCHEMBL1481339 | 0.78 | CES2 (0.80) | CES1CES2TSHRALDH1A1DAO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009150144-A1 | NEW GPR119MODULATORS | INOVACIA AB (SE) | 2009-12-17 | — | — | WO | disclosed |