SCHEMBL4354004

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL11003364	0.83	HPGD (0.46)	ALKBH5NPSR1HPGDHSD17B10POLB
	SCHEMBL11002564	0.78	ESR1 (0.43)	NPSR1HPGDHSD17B10POLBALDH1A1
	SCHEMBL11000015	0.77	KDM4E (0.45)	NPSR1HPGDHSD17B10POLBALDH1A1
	SCHEMBL11156275	0.76	HPGD (0.58)	ALKBH5NPSR1HPGDHSD17B10POLB
	SCHEMBL10921947	0.76	POLB (0.39)	NPSR1HPGDHSD17B10POLBMCL1
	SCHEMBL10998243	0.76	KDM4E (0.48)	NPSR1HPGDHSD17B10POLBMCL1
	SCHEMBL10922417	0.75	MCL1 (0.40)	ALKBH5NPSR1HPGDHSD17B10POLB
	SCHEMBL10924857	0.74	SCN2A (0.48)	HPGDHSD17B10POLBALDH1A1KDM4E
	SCHEMBL10999707	0.72	TDP1 (0.45)	POLBALDH1A1GAAPKMKMT2A
	SCHEMBL10920350	0.71	ALDH1A1 (0.43)	NPSR1HPGDHSD17B10POLBALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.