SCHEMBL4354095

SCHEMBL4354095

Cc1cc(Oc2cc(C)c(C(=O)O)c(C(=O)O)c2)cc(C(=O)O)c1C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 4/20 0.44
ALDH1A1 P00352 3/20 0.44
HPGD P15428 3/20 0.44
KMT2A Q03164 2/20 0.44
MAPK1 P28482 2/20 0.44
HSD17B10 Q99714 2/20 0.44
MEN1 O00255 1/20 0.44
ALOX15 P16050 1/20 0.44
POLB P06746 3/20 0.42
ACHE P22303 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.40
TDP1 Q9NUW8 1/20 0.38
NOTUM Q6P988 1/20 0.38
KDM4E B2RXH2 3/20 0.37
NR1H4 Q96RI1 1/20 0.37
MAPT P10636 1/20 0.37
GLO1 Q04760 1/20 0.36
GAA P10253 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5581309 0.87 CYP3A4 (0.49) CYP3A4ALDH1A1HPGDKMT2AMAPK1
SCHEMBL384123 0.86 POLB (0.57) CYP3A4ALDH1A1HPGDKMT2AMAPK1
SCHEMBL3387328 0.77 KDM4E (0.61) CYP3A4ALDH1A1HPGDMAPK1HSD17B10
SCHEMBL4659030 0.77 MCL1 (0.48) CYP3A4ALDH1A1HPGDKMT2AMAPK1
SCHEMBL4499664 0.76 MEN1 (0.56) KMT2AMEN1
SCHEMBL6334301 0.75 TPMT (0.48) CYP3A4ALDH1A1HPGDMAPK1HSD17B10
SCHEMBL9353947 0.75 CYP3A4 (0.67) CYP3A4ALDH1A1HPGDKMT2AMAPK1
SCHEMBL30263035 0.75 KDM4E (0.59) CYP3A4ALDH1A1HPGDKMT2AMAPK1
SCHEMBL1264866 0.74 CYP3A4 (0.65) CYP3A4ALDH1A1HPGDKMT2AMAPK1
SCHEMBL2529829 0.74 CYP3A4 (0.48) CYP3A4ALDH1A1HPGDKMT2AMAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1457511-B1 CROSSLINKABLE AROMATIC RESINS HAVING PROTONIC ACID GROUPS AND ION CONDUCTIVE POLYMER MEMBRANES BINDERS AND FUEL CELLS MADE BY USING THE SAME MITSUI CHEMICALS INC (JP) 2009-07-15 EP disclosed
US-7345135-B2 Crosslinkable aromatic resin having protonic acid group, and ion conductive polymer membrane, binder and fuel cell using the resin MITSUI CHEMICALS, INC. (JP) 2008-03-18 US disclosed
US-20040191602-A1 Crosslinkable aromatic resin having protonic acid group, and ion conductive polymer membrane, binder and fuel cell using the resin MITSUI CHEMICALS, INC. (JP) 2004-09-30 US disclosed
EP-1457511-A1 CROSSLINKABLE AROMATIC RESINS HAVING PROTONIC ACID GROUPS AND ION CONDUCTIVE POLYMER MEMBRANES BINDERS AND FUEL CELLS MADE BY USING THE SAME Mitsui Chemicals, Inc. (JP) 2004-09-15 EP disclosed