SCHEMBL4499664

SCHEMBL4499664

Cc1cc(OCc2ccccc2)cc(C(=O)O)c1C(=O)O

nearest known ligand 0.56

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 1/20 0.56
KMT2A Q03164 1/20 0.56
MRGPRX4 Q96LA9 2/20 0.52
MCL1 Q07820 3/20 0.50
MAOB P27338 3/20 0.50
NR4A2 P43354 2/20 0.50
CTSV O60911 1/20 0.50
CTSL P07711 1/20 0.50
NR4A1 P22736 1/20 0.50
NR4A3 Q92570 1/20 0.50
BAK1 Q16611 1/20 0.49
P4HTM Q9NXG6 1/20 0.49
FFAR1 O14842 1/20 0.47
ALKBH1 Q13686 2/20 0.47
SRD5A2 P31213 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL597702 0.91 MEN1 (0.63) MEN1KMT2AMRGPRX4MAOBNR4A2
SCHEMBL10659926 0.89 MEN1 (0.51) MEN1KMT2AMRGPRX4MCL1MAOB
SCHEMBL7921994 0.87 KMT2A (0.58) MEN1KMT2AMRGPRX4MCL1MAOB
SCHEMBL13965398 0.85 MEN1 (0.56) MEN1KMT2AMRGPRX4MCL1MAOB
SCHEMBL1842000 0.85 MEN1 (0.56) MEN1KMT2AMRGPRX4MCL1MAOB
SCHEMBL27489408 0.84 MEN1 (0.63) MEN1KMT2AMRGPRX4MCL1MAOB
SCHEMBL10657327 0.84 MEN1 (0.55) MEN1KMT2AMRGPRX4MCL1MAOB
SCHEMBL22490923 0.83 MEN1 (0.54) MEN1KMT2AMRGPRX4MAOBNR4A2
SCHEMBL1022035 0.82 MAOB (0.64) MEN1KMT2AMRGPRX4MCL1MAOB
Benzene SCHEMBL28056879 0.82 MAOB (0.64) MEN1KMT2AMRGPRX4MCL1MAOB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20090298894-A1 AMINO ACID COMPOUNDS ASAHI KASEI PHARMA CORPORATION (JP) 2009-12-03 US disclosed
US-4745116-A INHIBITORS OF SERINE PROTEASE SYNTEX (U.S.A.) INC. (US) 1988-05-17 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090298894-A1 AMINO ACID COMPOUNDS S1PR1, S1PR2, S1PR5 MEN1 1035/4885KMT2A 3063/4885MRGPRX4 121/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.