Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX7 | Q99572 | 9/20 | 0.52 |
| ▸ | HCN4 | Q9Y3Q4 | 4/20 | 0.51 |
| ▸ | HCN1 | O60741 | 4/20 | 0.51 |
| ▸ | HCN3 | Q9P1Z3 | 1/20 | 0.51 |
| ▸ | HCN2 | Q9UL51 | 1/20 | 0.51 |
| ▸ | IL1B | P01584 | 7/20 | 0.45 |
| ▸ | SLC6A9 | P48067 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4358768 | 0.91 | P2RX7 (0.52) | P2RX7HCN4HCN1HCN3HCN2 | |
| SCHEMBL4360116 | 0.90 | P2RX7 (0.49) | P2RX7HCN4HCN1HCN3HCN2 | |
| SCHEMBL4354507 | 0.89 | P2RX7 (0.48) | P2RX7HCN4HCN1HCN3HCN2 | |
| SCHEMBL4356281 | 0.89 | P2RX7 (0.48) | P2RX7HCN4HCN1HCN3HCN2 | |
| SCHEMBL13706887 | 0.89 | P2RX7 (0.48) | P2RX7HCN4HCN1HCN3HCN2 | |
| SCHEMBL4358152 | 0.88 | HCN4 (0.55) | P2RX7HCN4HCN1IL1BSLC6A9 | |
| SCHEMBL4351906 | 0.85 | P2RX7 (0.49) | P2RX7HCN4HCN1HCN3HCN2 | |
| SCHEMBL4541189 | 0.85 | P2RX7 (0.49) | P2RX7HCN4HCN1HCN3HCN2 | |
| SCHEMBL4351646 | 0.85 | P2RX7 (0.49) | P2RX7HCN4HCN1HCN3HCN2 | |
| SCHEMBL4359606 | 0.84 | P2RX7 (0.47) | P2RX7HCN4HCN1HCN3HCN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009108551-A2 | HETEROARYL AMIDE ANALOGUES | H. LUNDBECK A/S (DK) | 2009-09-03 | — | — | WO | claimed |
| WO-2009108551-A2 | HETEROARYL AMIDE ANALOGUES | H. LUNDBECK A/S (DK) | 2009-09-03 | — | — | WO | disclosed |