SCHEMBL4354660

SCHEMBL4354660

O=C(O)CCCC(=O)OF

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.58
SLC22A6 Q4U2R8 2/20 0.58
LMNA P02545 4/20 0.50
NFKB1 P19838 2/20 0.48
PMP22 Q01453 1/20 0.48
CAMK2A Q9UQM7 1/20 0.43
GABRR3 A8MPY1 1/20 0.42
GABRP O00591 1/20 0.42
GABRD O14764 1/20 0.42
HDAC3 O15379 1/20 0.42
GABBR2 O75899 1/20 0.42
CYP1A2 P05177 1/20 0.42
THRB P10828 1/20 0.42
GABRA1 P14867 1/20 0.42
GABRB1 P18505 1/20 0.42
GABRG2 P18507 1/20 0.42
GABRR1 P24046 1/20 0.42
GABRB3 P28472 1/20 0.42
GABRR2 P28476 1/20 0.42
SLC6A1 P30531 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8639485 0.92 TSHR (0.60) TSHRSLC22A6LMNANFKB1PMP22
SCHEMBL10635077 0.92 TSHR (0.60) TSHRSLC22A6LMNANFKB1PMP22
Ammonia Solution, Strong SCHEMBL28535380 0.90 TSHR (0.57) TSHRSLC22A6LMNANFKB1PMP22
Ammonia Solution, Strong SCHEMBL28644454 0.90 TSHR (0.57) TSHRSLC22A6LMNANFKB1PMP22
Ammonia Solution, Strong SCHEMBL28638205 0.90 TSHR (0.57) TSHRSLC22A6LMNANFKB1PMP22
Ammonia Solution, Strong SCHEMBL28551895 0.90 TSHR (0.57) TSHRSLC22A6LMNANFKB1PMP22
SCHEMBL20552948 0.89 TSHR (0.50) TSHRSLC22A6LMNACYP1A2KMT2A
Hydrochloric Acid SCHEMBL8005039 0.81 LMNA (0.50) TSHRSLC22A6LMNANFKB1PMP22
Acrylic Acid SCHEMBL30411952 0.81 ABCC4 (0.48) TSHRSLC22A6LMNANFKB1PMP22
SCHEMBL312723 0.78 SLC22A6 (0.65) TSHRSLC22A6LMNANFKB1PMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102741264-A Prostate specific membrane antigen inhibitors BAYER SCHERING PHARMA AG 2012-10-17 CN disclosed
US-20090311498-A1 Transparent conductive film KONICA MINOLTA HOLDINGS, INC. (JP) 2009-12-17 US disclosed
EP-1796108-A1 TRANSPARENT CONDUCTIVE FILM KONICA MINOLTA HOLDINGS, INC. (JP) 2007-06-13 EP disclosed
EP-1481802-B1 Directly imageable planographic printing plate precursor and a method of producing planographic printing plate TORAY INDUSTRIES (JP) 2006-09-20 EP disclosed
EP-0914942-B1 Directly imageable waterless planographic printing plate precursor and a method of producing planographic printing plates TORAY INDUSTRIES (JP) 2005-05-25 EP disclosed
EP-1481802-A1 Directly imageable planographic printing plate precursor and a method of producing planographic printing plate TORAY INDUSTRIES, INC. (JP) 2004-12-01 EP disclosed
EP-1046496-B1 Planographic printing plate precursor containing metal compounds, and process for producing planographic printing plates FUJI PHOTO FILM CO LTD (JP) 2004-02-18 EP disclosed
US-6420083-B1 EXCELLENT SENSITIVITY; DOES NOT REQUIRE WET DEVELOPMENT; HYDROPHILIC GROUPS IN POLYMER COORDINATE WITH THE POLYVALENT METAL CATION RELEASED BY HEAT AND FORM A HYDROPHOBIC POLYMER FUJI PHOTO FILM CO., LTD. (JP) 2002-07-16 US disclosed
EP-1046496-A1 Planographic printing plate precursor containing metal compounds, and process for producing planographic printing plates FUJI PHOTO FILM CO., LTD. (JP) 2000-10-25 EP disclosed
EP-0914942-A2 Directly imageable waterless planographic printing plate precursor and a method of producing planographic printing plates TORAY INDUSTRIES, INC. (JP) 1999-05-12 EP disclosed