Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CG | P48736 | 9/20 | 0.63 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.59 |
| ▸ | PIK3CB | P42338 | 3/20 | 0.59 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.59 |
| ▸ | PIK3C2B | O00750 | 1/20 | 0.59 |
| ▸ | PDXK | O00764 | 1/20 | 0.59 |
| ▸ | GAK | O14976 | 1/20 | 0.59 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.59 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.59 |
| ▸ | PIP5K1C | O60331 | 1/20 | 0.59 |
| ▸ | STK16 | O75716 | 1/20 | 0.59 |
| ▸ | PIK3C2G | O75747 | 1/20 | 0.59 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.59 |
| ▸ | OXSR1 | O95747 | 1/20 | 0.59 |
| ▸ | LATS1 | O95835 | 1/20 | 0.59 |
| ▸ | ABL1 | P00519 | 1/20 | 0.59 |
| ▸ | EGFR | P00533 | 1/20 | 0.59 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.59 |
| ▸ | LCK | P06239 | 1/20 | 0.59 |
| ▸ | BRAF | P15056 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12068878 | 0.81 | PIK3CG (0.55) | PIK3CGJAK1TYK2ADORA1ADORA2A | |
| SCHEMBL14983456 | 0.79 | PIK3CG (0.62) | PIK3CGCLK1ADORA1ADORA2AADORA2B | |
| SCHEMBL13019165 | 0.79 | PIK3CG (0.63) | PIK3CGPIK3CAPIK3CBPIK3CDPIK3C2B | |
| Hydrochloric Acid SCHEMBL3741616 | 0.78 | PIK3CG (0.61) | PIK3CGPIK3CAPIK3CBPIK3CDPIK3C2B | |
| SCHEMBL27632005 | 0.76 | ADORA1 (0.62) | PIK3CGPIK3CAPIK3CBPIK3CDPIK3C2B | |
| Tg100-115 SCHEMBL29506727 | 0.75 | PIK3CG (1.00) | PIK3CGPIK3CAPIK3CBPIK3CDPIK3C2B | |
| SCHEMBL12198179 | 0.75 | PIK3CG (0.78) | PIK3CGPIK3CAPIK3CBPIK3CDPIK3C2B | |
| Tg100-115 SCHEMBL360279 | 0.75 | PIK3CG (1.00) | PIK3CGPIK3CAPIK3CBPIK3CDPIK3C2B | |
| Tg100-115 SCHEMBL29369340 | 0.75 | PIK3CG (1.00) | PIK3CGPIK3CAPIK3CBPIK3CDPIK3C2B | |
| Tg100-115 SCHEMBL29411790 | 0.75 | PIK3CG (1.00) | PIK3CGPIK3CAPIK3CBPIK3CDPIK3C2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2039683-B1 | Vasculostatic agents and methods of use thereof | TARGEGEN INC (US) | 2012-12-19 | — | — | EP | disclosed |
| EP-2039683-A2 | Vasculostatic agents and methods of use thereof | Targegen, Inc. (US) | 2009-03-25 | — | — | EP | disclosed |