SCHEMBL4355034

SCHEMBL4355034

OCCc1c2ccccc2c(Br)c2ccccc12

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.46
TSHR P16473 1/20 0.46
HTT P42858 1/20 0.46
TDP1 Q9NUW8 1/20 0.42
HPGD P15428 2/20 0.41
HSD17B10 Q99714 1/20 0.41
POLB P06746 3/20 0.36
KDM4E B2RXH2 3/20 0.36
HSP90AA1 P07900 1/20 0.36
HNF4A P41235 1/20 0.36
GAA P10253 4/20 0.33
FOLH1 Q04609 1/20 0.31
RAD52 P43351 2/20 0.31
CA2 P00918 1/20 0.31
IDO1 P14902 2/20 0.31
TDO2 P48775 1/20 0.31
MITF O75030 1/20 0.31
LMNA P02545 1/20 0.31
TTR P02766 1/20 0.31
GLA P06280 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2314302 0.90 ALDH1A1 (0.52) ALDH1A1TSHRHTTTDP1HPGD
SCHEMBL1072230 0.83 DRD4 (0.37) ALDH1A1TSHRHTTHPGDHSD17B10
SCHEMBL10733752 0.82 ALDH1A1 (0.50) ALDH1A1TSHRHTTTDP1HPGD
SCHEMBL8376185 0.77 TDP1 (0.45) ALDH1A1TSHRHTTTDP1KDM4E
SCHEMBL13430090 0.76 FOLH1 (0.41) ALDH1A1HPGDPOLBKDM4EGAA
SCHEMBL28511 0.76 ALDH1A1 (0.44) ALDH1A1TSHRTDP1HSD17B10POLB
SCHEMBL29352635 0.76 ALDH1A1 (0.44) ALDH1A1TSHRTDP1HSD17B10POLB
SCHEMBL5152473 0.76 TDP1 (0.34) ALDH1A1TSHRHTTTDP1
SCHEMBL13815223 0.75 ALDH1A1 (0.38) ALDH1A1TSHRTDP1HPGDPOLB
SCHEMBL240651 0.74 HTR2A (0.56) ALDH1A1TSHRHTTTDP1HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7635571-B2 photosenstizer generates singlet oxygen which oxidatively cleaves the linker to form a product which can be detected in a sandwich detection assay; kits SIEMENS HEALTHCARE DIAGNOSTICS PRODUCTS GMBH (DE) 2009-12-22 US disclosed
US-7635571-B2 photosenstizer generates singlet oxygen which oxidatively cleaves the linker to form a product which can be detected in a sandwich detection assay; kits SIEMENS HEALTHCARE DIAGNOSTICS PRODUCTS GMBH (DE) 2009-12-22 US disclosed
US-7635571-B2 photosenstizer generates singlet oxygen which oxidatively cleaves the linker to form a product which can be detected in a sandwich detection assay; kits SIEMENS HEALTHCARE DIAGNOSTICS PRODUCTS GMBH (DE) 2009-12-22 US disclosed
US-20040175696-A1 Amplified luminescent homogeneous immunoassay SIEMENS HEALTHCARE DIAGNOSTICS PRODUCTS GMBH (DE) 2004-09-09 US disclosed
EP-1179025-A1 SUPPORTED CATALYSTS AND OLEFIN POLYMERIZATION PROCESSES UTILIZING SAME Cryovac, Inc. (US) 2002-02-13 EP disclosed
EP-1171481-A1 SUPPORTED CATALYSTS AND OLEFIN POLYMERIZATION PROCESSES UTILIZING SAME Cryovac, Inc. (US) 2002-01-16 EP disclosed
US-6197714-B1 USEFUL IN SLURRY AND GAS PHASE POLYMERIZATION OF OLEFINS CRYOVAC, INC. 2001-03-06 US disclosed
US-6197715-B1 USEFUL IN SLURRY AND GAS PHASE POLYMERIZATION OF OLEFINS CRYOVAC, INC. 2001-03-06 US disclosed
WO-2000056787-A1 SUPPORTED CATALYSTS AND OLEFIN POLYMERIZATION PROCESSES UTILIZING SAME CRYOVAC, INC. (US) 2000-09-28 WO disclosed
WO-2000056786-A1 SUPPORTED CATALYSTS AND OLEFIN POLYMERIZATION PROCESSES UTILIZING SAME CRYOVAC, INC. (US) 2000-09-28 WO disclosed