Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 3/20 | 0.70 |
| ▸ | KMO | O15229 | 1/20 | 0.67 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.64 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.64 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.64 |
| ▸ | PARP1 | P09874 | 6/20 | 0.62 |
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 1/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | RECQL | P46063 | 1/20 | 0.62 |
| ▸ | BLM | P54132 | 1/20 | 0.62 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.62 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.60 |
| ▸ | ERN1 | O75460 | 1/20 | 0.57 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29788172 | 1.00 | DHODH (0.70) | DHODHKMOPRSS1PRSS2PRSS3 | |
| Bromide SCHEMBL30159854 | 0.98 | DHODH (0.68) | DHODHKMOPRSS1PRSS2PRSS3 | |
| Hydrogen Sulfide SCHEMBL27914334 | 0.98 | DHODH (0.68) | DHODHKMOPRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL3973404 | 0.98 | DHODH (0.68) | DHODHKMOPRSS1PRSS2PRSS3 | |
| SCHEMBL29941476 | 0.98 | DHODH (0.68) | DHODHKMOPRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL30628442 | 0.98 | DHODH (0.68) | DHODHKMOPRSS1PRSS2PRSS3 | |
| SCHEMBL6999225 | 0.96 | DHODH (0.63) | DHODHKMOPRSS1PRSS2PRSS3 | |
| SCHEMBL2431097 | 0.93 | PARP1 (0.64) | DHODHKMOPRSS1PRSS2PRSS3 | |
| SCHEMBL31422694 | 0.93 | PARP1 (0.64) | DHODHKMOPRSS1PRSS2PRSS3 | |
| Phosphoric Acid SCHEMBL19385047 | 0.92 | DHODH (0.62) | DHODHKMOPRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 401 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024259171-A9 | KEAP1 INHIBITORS AND USES THEREOF | VIVIDION THERAPEUTICS, INC. (US) | 2025-01-23 | — | — | WO | claimed |
| CN-119192174-A | Novel biphenyl carboxylic FXR agonist, preparation method thereof and application thereof as medicine | 广东药科大学 | 2024-12-27 | — | — | CN | claimed |
| CN-119186425-A | Micro-reactor reaction channel structure, preparation method, preparation system and application of solid acid catalyst | 中国石油化工股份有限公司 | 2024-12-27 | — | — | CN | claimed |
| CN-119192440-A | Butene hydration catalyst and preparation method and application thereof | 中国石油化工股份有限公司 | 2024-12-27 | — | — | CN | claimed |
| US-12168014-B2 | Method for treating cancer | Epizyme, Inc. (US) | 2024-12-17 | — | — | US | claimed |
| WO-2024146870-A1 | COMPOSITIONS FOR HORMONALLY IMPACTED SKIN | THE BOOTS COMPANY PLC (GB) | 2024-07-11 | — | — | WO | claimed |
| CN-118206465-A | Novel biphenyl carboxylic acid FABP1 inhibitor, preparation method thereof and application thereof as medicine | 广东药科大学 | 2024-06-18 | — | — | CN | claimed |
| WO-2024121709-A1 | PAPAIN-LIKE PROTEASE (PLPRO) INHIBITORS | PFIZER INC. (US) | 2024-06-13 | — | — | WO | claimed |
| CN-118076602-A | Heteroaryl-acetylenes, pharmaceutical compositions thereof and their therapeutic uses | 嘉兴优博生物技术有限公司 | 2024-05-24 | — | — | CN | claimed |
| CN-114630819-B | Benzamide derivative for preventing or treating cancer, method for preparing the same, and pharmaceutical composition comprising the same as active ingredient | 韩国化学研究院 | 2024-02-13 | — | — | CN | claimed |
| WO-2005021558-A2 | PROTEASOME INHIBITORS AND METHODS OF USING THE SAME | CEPHALON, INC. (US) | 2005-03-10 | — | — | WO | claimed |
| EP-1509497-A1 | CALCIUM RECEPTOR MODULATING ARYLALKYLAMINES | Amgen Inc. (US) | 2005-03-02 | — | — | EP | claimed |
| WO-2004099127-A1 | NOVEL COMPOUNDS AS KINASE INHIBITORS | NOVO NORDISK A/S (DK) | 2004-11-18 | — | — | WO | claimed |
| WO-2004093872-A1 | 3-OXO-1, 3-DIHYDRO-INDAZOLE-2-CARBOXYLIC ACID AMIDE DERIVATIVES AS PHOSPHOLIPASE INHIBITORS | ELI LILLY AND COMPANY (US) | 2004-11-04 | — | — | WO | claimed |
| EP-1453789-A2 | N,N'-SUBSTITUTED-1,3-DIAMINO-2-HYDROXYPROPANE DERIVATIVES | Elan Pharmaceuticals, Inc. (US) | 2004-09-08 | — | — | EP | claimed |
| WO-2003099776-A1 | CALCIUM RECEPTOR MODULATING ARYLALKYLAMINES | AMGEN INC. (US) | 2003-12-04 | — | — | WO | claimed |
| WO-2003040096-A2 | N, N'-SUBSTITUTED-1,3-DIAMINO-2-HYDROXYPROPANE DERIVATIVES | ELAN PHARMACEUTICALS, INC. (US) | 2003-05-15 | — | — | WO | claimed |
| CN-1400973-A | Novel biarylcarboxamides | ASTRAZENECA AB (SE) | 2003-03-05 | — | — | CN | claimed |
| EP-0460083-A1 | DERIVATIVES OF N-PHENYLBENZAMIDE WITH ANTI-ULCER AND ANTI-ALLERGY ACTIVITY AND A METHOD FOR THEIR PREPARATION. | ROTTA RESEARCH LAB (IT) | 1991-12-11 | — | — | EP | claimed |
| WO-1990009989-A1 | DERIVATIVES OF N-PHENYLBENZAMIDE WITH ANTI-ULCER AND ANTI-ALLERGY ACTIVITY AND A METHOD FOR THEIR PREPARATION | ROTTA RESEARCH LABORATORIUM S.P.A. (IT) | 1990-09-07 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12168014-B2 | Method for treating cancer | EZH2, BMI1, EZH1 | DHODH 1954/4885KMO 3473/4885PRSS1 2584/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.