Styrene

Styrene

SCHEMBL4355403

C=C(C)C(=O)OCCOC(=O)C(=C)C.C=CC(=O)OCCCC.C=Cc1ccccc1

nearest known ligand 0.54

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 7/20 0.54
HPGD P15428 1/20 0.54
THRB P10828 6/20 0.47
TDP1 Q9NUW8 4/20 0.44
POLB P06746 1/20 0.44
APEX1 P27695 1/20 0.44
HTT P42858 1/20 0.44
KDM4E B2RXH2 1/20 0.42
THRA P10827 1/20 0.41
L3MBTL1 Q9Y468 2/20 0.40
CYP3A4 P08684 3/20 0.40
ALDH1A1 P00352 2/20 0.40
ATM Q13315 1/20 0.39
HCAR2 Q8TDS4 1/20 0.38
APP P05067 1/20 0.38
MAPK1 P28482 2/20 0.38
TP53 P04637 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Styrene SCHEMBL6283469 0.99 TSHR (0.55) TSHRHPGDTHRBTDP1POLB
Styrene SCHEMBL8763825 0.96 TSHR (0.52) TSHRHPGDTHRBTDP1POLB
Styrene SCHEMBL7903211 0.96 TSHR (0.52) TSHRHPGDTHRBTDP1POLB
Styrene SCHEMBL6653463 0.94 THRB (0.50) TSHRHPGDTHRBTDP1POLB
Styrene SCHEMBL8998290 0.94 TSHR (0.50) TSHRHPGDTHRBTDP1POLB
Styrene SCHEMBL9751701 0.94 TSHR (0.50) TSHRHPGDTHRBTDP1POLB
Styrene SCHEMBL10906592 0.94 TSHR (0.50) TSHRHPGDTHRBTDP1POLB
Styrene SCHEMBL891201 0.94 TSHR (0.50) TSHRHPGDTHRBTDP1POLB
Styrene SCHEMBL8321010 0.94 TSHR (0.50) TSHRHPGDTHRBTDP1POLB
Styrene SCHEMBL28489056 0.94 TSHR (0.49) TSHRHPGDTHRBTDP1POLB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1193078-B1 Ink jet image recording method FUJIFILM CORP (JP) 2009-04-15 EP disclosed
US-6604819-B2 Ink jet image recording method FUJI PHOTO FILM CO., LTD. (JP) 2003-08-12 US disclosed
EP-1193078-A2 Ink jet image recording method FUJI PHOTO FILM CO., LTD. (JP) 2002-04-03 EP disclosed