Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR3A | P46098 | 11/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | MC4R | P32245 | 1/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.38 |
| ▸ | MC3R | P41968 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CDC7 | O00311 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15557435 | 0.88 | HTR3A (0.56) | HTR3AKDM4ENR4A2 | |
| SCHEMBL17176399 | 0.86 | HTR3A (0.57) | HTR3AKDM4EHTTTSHRNR4A2 | |
| SCHEMBL17170671 | 0.83 | HTR3A (0.57) | HTR3AHTTTSHRNR4A2L3MBTL1 | |
| SCHEMBL19969879 | 0.83 | HTR3A (0.54) | HTR3ATSHRL3MBTL1 | |
| SCHEMBL4368383 | 0.83 | PDE4A (0.47) | HTR3AKDM4EHTT | |
| SCHEMBL30417766 | 0.82 | HTR3A (0.51) | HTR3AKDM4E | |
| SCHEMBL4351538 | 0.79 | HTR3A (0.50) | HTR3AKDM4ENR4A2L3MBTL1 | |
| SCHEMBL21249088 | 0.76 | RPS6KA5 (0.45) | KDM4EL3MBTL1CDC7CDK2 | |
| SCHEMBL30647411 | 0.76 | RPS6KA5 (0.45) | KDM4EL3MBTL1CDC7CDK2 | |
| SCHEMBL30416390 | 0.75 | HTR3A (0.52) | HTR3AKDM4ETSHRL3MBTL1CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009108551-A2 | HETEROARYL AMIDE ANALOGUES | H. LUNDBECK A/S (DK) | 2009-09-03 | — | — | WO | disclosed |