SCHEMBL4355800

SCHEMBL4355800

N#CC1(N)CCCCCC1

nearest known ligand 0.46

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.46
KDM4E B2RXH2 1/20 0.31
MAPT P10636 1/20 0.31
TSHR P16473 1/20 0.31
CYP2C19 P33261 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20987612 1.00 ALDH1A1 (0.46) ALDH1A1KDM4EMAPTTSHRCYP2C19
SCHEMBL23311387 1.00 ALDH1A1 (0.46) ALDH1A1KDM4EMAPTTSHRCYP2C19
SCHEMBL20987611 1.00 ALDH1A1 (0.46) ALDH1A1KDM4EMAPTTSHRCYP2C19
SCHEMBL420103 1.00
Hydrochloric Acid SCHEMBL696355 0.97 ALDH1A1 (0.43) ALDH1A1KDM4EMAPT
SCHEMBL75984 0.97
Hydrochloric Acid SCHEMBL56064 0.94
SCHEMBL1139426 0.90
Hydrochloric Acid SCHEMBL695268 0.88
Oxalic Acid SCHEMBL27896638 0.85 ALDH1A1 (0.41) ALDH1A1TSHRCYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009108551-A2 HETEROARYL AMIDE ANALOGUES H. LUNDBECK A/S (DK) 2009-09-03 WO disclosed
WO-2009108551-A2 HETEROARYL AMIDE ANALOGUES H. LUNDBECK A/S (DK) 2009-09-03 WO disclosed