Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCN4 | Q9Y3Q4 | 14/20 | 0.52 |
| ▸ | HCN1 | O60741 | 12/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4350518 | 0.92 | HCN4 (0.51) | HCN4HCN1P2RX7 | |
| SCHEMBL4364182 | 0.88 | HCN4 (0.56) | HCN4HCN1ALDH1A1TSHRP2RX7 | |
| SCHEMBL4358868 | 0.83 | HCN4 (0.58) | HCN4HCN1P2RX7TP53 | |
| SCHEMBL4351540 | 0.83 | HCN4 (0.58) | HCN4HCN1P2RX7TP53 | |
| SCHEMBL4358152 | 0.82 | HCN4 (0.55) | HCN4HCN1P2RX7 | |
| SCHEMBL13706748 | 0.82 | HCN4 (0.51) | HCN4HCN1P2RX7 | |
| SCHEMBL13706884 | 0.80 | HCN4 (0.52) | HCN4HCN1P2RX7 | |
| SCHEMBL13706775 | 0.80 | HCN4 (0.50) | HCN4HCN1P2RX7 | |
| SCHEMBL4360116 | 0.80 | P2RX7 (0.49) | HCN4HCN1ALDH1A1TSHRP2RX7 | |
| SCHEMBL13706796 | 0.80 | HCN4 (0.56) | HCN4HCN1ALDH1A1TSHRTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009108551-A2 | HETEROARYL AMIDE ANALOGUES | H. LUNDBECK A/S (DK) | 2009-09-03 | — | — | WO | claimed |