SCHEMBL4356111

SCHEMBL4356111

C#CCn1nnc(-c2ccc(N3C[C@H](CNC(C)=O)OC3=O)cc2F)n1

nearest known ligand 0.61

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
MAOA P21397 7/20 0.61
MAOB P27338 4/20 0.55
CALML3 P27482 4/20 0.55
PTGS1 P23219 2/20 0.55
SDHA P31040 2/20 0.55
LMNA P02545 1/20 0.55

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4153669 0.92 MAOA (0.61) MAOAMAOBCALML3PTGS1SDHA
SCHEMBL13809656 0.90 MAOA (0.62) MAOAMAOBCALML3PTGS1SDHA
SCHEMBL4155760 0.89 MAOA (0.61) MAOAMAOBCALML3PTGS1SDHA
SCHEMBL13809401 0.89 MAOA (0.61) MAOAMAOBCALML3PTGS1SDHA
SCHEMBL4362283 0.88 MAOA (0.60) MAOAMAOBCALML3PTGS1SDHA
SCHEMBL13809667 0.87 MAOA (0.65) MAOAMAOBCALML3PTGS1SDHA
SCHEMBL13809913 0.87 MAOA (0.59) MAOAMAOBCALML3PTGS1SDHA
SCHEMBL2895216 0.85 MAOA (0.65) MAOAMAOBCALML3PTGS1SDHA
SCHEMBL4364246 0.84 MAOA (0.62) MAOAMAOBCALML3PTGS1SDHA
SCHEMBL3328441 0.83 MAOA (0.76) MAOAMAOBCALML3PTGS1SDHA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2009077485-A2 1(2)H-TETRAZOL-5-YL-PHENYL-OXAZOLIDINONES AS ANTIBACTERIAL AGENTS FERRER INTERNACIONAL, S.A. (ES) 2009-06-25 WO disclosed
EP-2072514-A1 1(2)H-tetrazol-5-yl-phenyl-oxazolidinones as antibacterial agents Ferrer Internacional, S.A. (ES) 2009-06-24 EP disclosed
EP-2072514-A1 1(2)H-tetrazol-5-yl-phenyl-oxazolidinones as antibacterial agents Ferrer Internacional, S.A. (ES) 2009-06-24 EP disclosed