⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1129124 | 0.84 | XDH (0.33) | — | |
| SCHEMBL4357630 | 0.77 | NTRK1 (0.34) | — | |
| SCHEMBL4354256 | 0.76 | TNK2 (0.33) | — | |
| SCHEMBL4361634 | 0.75 | — | — | |
| SCHEMBL4369154 | 0.75 | TNK2 (0.32) | — | |
| SCHEMBL4360771 | 0.74 | TNK2 (0.35) | — | |
| SCHEMBL1128753 | 0.72 | TNK2 (0.41) | — | |
| SCHEMBL4357435 | 0.72 | TNK2 (0.31) | — | |
| SCHEMBL4368949 | 0.71 | TNK2 (0.34) | — | |
| SCHEMBL4358948 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283020-B1 | SUBSTITUTED IMIDAZOPYR-AND IMIDAZOTRI-AZINES | OSI PHARM INC (US) | 2012-10-31 | — | — | EP | claimed |
| US-8481733-B2 | Substituted imidazopyr- and imidazotri-azines | OSI Pharmaceuticals, LLC (US) | 2013-07-09 | — | — | US | disclosed |
| EP-2283020-B1 | SUBSTITUTED IMIDAZOPYR-AND IMIDAZOTRI-AZINES | OSI PHARM INC (US) | 2012-10-31 | — | — | EP | disclosed |
| US-20090286768-A1 | SUBSTITUTED IMIDAZOPYR- AND IMIDAZOTRI-AZINES | OSI PHARMACEUTICALS, INC. (US) | 2009-11-19 | — | — | US | disclosed |