Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 3/20 | 0.54 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.53 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.53 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.53 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.53 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.53 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.53 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.53 |
| ▸ | FDPS | P14324 | 1/20 | 0.44 |
| ▸ | PTPRA | P18433 | 1/20 | 0.44 |
| ▸ | DPP4 | P27487 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LIN28A | Q9H9Z2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30819042 | 1.00 | HRH1 (0.54) | HRH1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL27484479 | 0.89 | GRIN2D (0.56) | HRH1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL28581360 | 0.85 | GRIN2D (0.51) | HRH1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL20278959 | 0.85 | GRIN2D (0.51) | HRH1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL16830441 | 0.84 | HRH1 (0.56) | HRH1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL6997949 | 0.83 | GRIN2D (0.66) | HRH1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL22118359 | 0.82 | GRIN2D (0.49) | HRH1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL230643 | 0.82 | GRIN2D (0.59) | HRH1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL20279216 | 0.81 | GRIN2D (0.54) | HRH1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL20099916 | 0.81 | GRIN2D (0.54) | HRH1GRIN2DGRIN3BGRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111801102-B | Methods and compositions for forming copper-containing complexes and uses thereof | 冷泉港实验室 | 2024-05-28 | — | — | CN | disclosed |
| CN-112867728-B | Copper-chelated (pyridylmethylene) butanediamine derivatives | 冷泉港实验室 | 2024-04-05 | — | — | CN | disclosed |
| CN-112867728-A | Copper chelated (pyridylmethylene) butanediamine derivatives | 冷泉港实验室 | 2021-05-28 | — | — | CN | disclosed |
| EP-3823977-A1 | (PYRIDINYLMETHYL)BUTANEDIAMINE DERIVATIVES THAT CHELATE COPPER | Cold Spring Harbor Laboratory (US) | 2021-05-26 | — | — | EP | disclosed |
| US-20200376006-A1 | METHOD AND COMPOSITIONS FOR FORMING A COPPER-CONTAINING COMPLEX AND USES THEREOF | COLD SPRING HARBOR LABORATORY (US) | 2020-12-03 | — | — | US | disclosed |
| EP-3706757-A1 | METHOD AND COMPOSITIONS FOR FORMING A COPPER-CONTAINING COMPLEX AND USES THEREOF | Cold Spring Harbor Laboratory (US) | 2020-09-16 | — | — | EP | disclosed |
| WO-2020018893-A1 | (PYRIDINYLMETHYL)BUTANEDIAMINE DERIVATIVES THAT CHELATE COPPER | COLD SPRING HARBOR LABORATORY (US) | 2020-01-23 | — | — | WO | disclosed |
| EP-1613613-A4 | CXCR4 CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC (CA) | 2009-03-25 | — | — | EP | disclosed |
| EP-1613613-A2 | CXCR4 CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC. (CA) | 2006-01-11 | — | — | EP | disclosed |
| WO-2004091518-A2 | CXCR4 CHEMOKINE RECEPTOR BINDING COMPOUNDS | ANORMED INC. (CA) | 2004-10-28 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200376006-A1 | METHOD AND COMPOSITIONS FOR FORMING A COPPER-CONTAINING COMPLEX AND USES THEREOF | PDXK, DMPK, CSNK1A1 | HRH1 1673/4885GRIN2D 2540/4885GRIN3B 689/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.