Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | GSK3A | P49840 | 2/20 | 0.35 |
| ▸ | GSK3B | P49841 | 2/20 | 0.35 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.35 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.35 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL9756583 | 0.98 | TSHR (0.47) | TSHRSMN1; SMN2GAAMEN1LMNA | |
| SCHEMBL20749289 | 0.86 | TSHR (0.55) | TSHRSMN1; SMN2GAAMEN1LMNA | |
| SCHEMBL10144466 | 0.82 | SMN1; SMN2 (0.51) | TSHRSMN1; SMN2GAAMEN1LMNA | |
| SCHEMBL395453 | 0.82 | — | — | |
| SCHEMBL487279 | 0.80 | SMN1; SMN2 (0.50) | TSHRSMN1; SMN2GAAMEN1LMNA | |
| Hydrochloric Acid SCHEMBL1198703 | 0.80 | TSHR (0.42) | TSHRSMN1; SMN2GAAMEN1LMNA | |
| Hydrochloric Acid SCHEMBL28008157 | 0.80 | TSHR (0.42) | TSHRSMN1; SMN2GAAMEN1LMNA | |
| SCHEMBL18772798 | 0.78 | SMN1; SMN2 (0.49) | TSHRSMN1; SMN2GAAMEN1LMNA | |
| SCHEMBL4353619 | 0.78 | TSHR (0.53) | TSHRSMN1; SMN2GAAMEN1LMNA | |
| SCHEMBL21888797 | 0.78 | TSHR (0.49) | TSHRSMN1; SMN2GAAMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009111540-A1 | METHODS FOR PREPARING PYRIDYLETHYL-SUBSTITUTED CARBOLINES | MEDIVATION NEUROLOGY, INC. (US) | 2009-09-11 | — | — | WO | disclosed |
| US-3969526-A | Anthelmintic 5-heterocycliothio and oxy-2-carbalkoxyaminobenzimidazles | SMITHKLINE CORPORATION (US) | 1976-07-13 | — | — | US | disclosed |