Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.45 |
| ▸ | RAB9A | P51151 | 4/20 | 0.45 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20749289 | 0.88 | TSHR (0.55) | SMN1; SMN2TSHRGAAMEN1LMNA | |
| SCHEMBL1971057 | 0.87 | NFKB1 (0.56) | SMN1; SMN2TSHRGAAMEN1LMNA | |
| SCHEMBL10347282 | 0.85 | L3MBTL1 (0.56) | SMN1; SMN2TSHRGAAMEN1LMNA | |
| SCHEMBL30665032 | 0.85 | L3MBTL1 (0.56) | SMN1; SMN2TSHRGAAMEN1LMNA | |
| SCHEMBL10144466 | 0.84 | SMN1; SMN2 (0.51) | SMN1; SMN2TSHRGAAMEN1LMNA | |
| SCHEMBL23011835 | 0.84 | RAB9A (0.55) | SMN1; SMN2TSHRGAAMEN1LMNA | |
| SCHEMBL487755 | 0.84 | RAB9A (0.55) | SMN1; SMN2TSHRGAAMEN1LMNA | |
| SCHEMBL27433082 | 0.84 | IDO1 (0.45) | SMN1; SMN2TSHRGAAMEN1KMT2A | |
| SCHEMBL17058993 | 0.84 | RAB9A (0.55) | SMN1; SMN2TSHRGAAMEN1LMNA | |
| SCHEMBL31189295 | 0.82 | GAA (0.55) | SMN1; SMN2TSHRGAAMEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9328126-B2 | Norbornenylhydrocarbylene dihydrocarbylboranes and methods of making the same | PROMERUS, LLC (US) | 2016-05-03 | — | — | US | claimed |
| US-20150353582-A1 | NORBORNENYLHYDROCARBYLENE DIHYDROCARBYLBORANES AND METHODS OF MAKING THE SAME | PROMERUS, LLC (US) | 2015-12-10 | — | — | US | claimed |
| WO-2014121008-A1 | NORBORNENYLHYDROCARBYLENE DIHYDROCARBYLBORANES AND METHODS OF MAKING THE SAME | PROMERUS, LLC (US) | 2014-08-07 | — | — | WO | claimed |
| US-8106200-B2 | Pyridine borane complexes | BASF SE (DE) | 2012-01-31 | — | — | US | claimed |
| US-20110207934-A1 | PYRIDINE BORANE COMPLEXES | BASF SE (DE) | 2011-08-25 | — | — | US | claimed |
| EP-2066631-B1 | PYRIDINE BORANE COMPLEXES | BASF SE (DE) | 2011-04-06 | — | — | EP | claimed |
| US-11833229-B2 | Labeling precursors with squaric acid coupling | SCV SPEZIAL-CHEMIKALIEN-VERTRIEBS GMBH (DE) | 2023-12-05 | — | — | US | disclosed |
| WO-2020155931-A1 | JAK INHIBITOR AND PREPARATION METHOD THEREFOR | 格格巫（珠海）生物科技有限公司 | 2020-08-06 | — | — | WO | disclosed |
| US-10660877-B2 | Pyridyl substituted indole compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 2020-05-26 | — | — | US | disclosed |
| US-20190262311-A1 | PYRIDYL SUBSTITUTED INDOLE COMPOUNDS | BRISTOL MYERS SQUIBB CO (US) | 2019-08-29 | — | — | US | disclosed |
| WO-2018128720-A1 | URACIL CONTAINING COMPOUNDS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-07-12 | — | — | WO | disclosed |
| EP-2968288-B1 | INHIBITORS OF THE RENAL OUTER MEDULLARY POTASSIUM CHANNEL | MERCK SHARP & DOHME (US) | 2018-07-04 | — | — | EP | disclosed |
| US-20170296539-A1 | COMPOSITE PREPARATION, CONTAINING NOVEL 3-(4--(BENZYLOXY)PHENYL)HEX-4-INOIC ACID DERIVATIVE AND ANOTHER ACTIVE INGREDIENT, FOR PREVENTING OR TREATING METABOLIC DISEASES | HYUNDAI PHARM CO., LTD. (KR) | 2017-10-19 | — | — | US | disclosed |
| EP-2066631-A1 | PYRIDINE BORANE COMPLEXES | BASF SE (DE) | 2009-06-10 | — | — | EP | disclosed |
| US-20090042919-A1 | METHOD FOR MODULATING GPR119 G PROTEIN-COUPLED RECEPTOR AND SELECTED COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY | 2009-02-12 | — | — | US | disclosed |
| US-20090042919-A1 | METHOD FOR MODULATING GPR119 G PROTEIN-COUPLED RECEPTOR AND SELECTED COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY | 2009-02-12 | — | — | US | disclosed |
| WO-2009012277-A1 | METHOD FOR MODULATING GPR119 G PROTEIN-COUPLED RECEPTOR AND SELECTED COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2009-01-22 | — | — | WO | disclosed |
| WO-2008055859-A1 | DIALKYLBORANE AMINE COMPLEXES | BASF SE (DE) | 2008-05-15 | — | — | WO | disclosed |
| WO-2008034886-A1 | PYRIDINE BORANE COMPLEXES | BASF SE (DE) | 2008-03-27 | — | — | WO | disclosed |
| US-5009799-A | Ethoxylated fatty amine and betaine inner salts, alkyne radical contining alcohol, pyridine quaternary ammonium salt | NALCO CHEMICAL COMPANY (US) | 1991-04-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090042919-A1 | METHOD FOR MODULATING GPR119 G PROTEIN-COUPLED RECEPTOR AND SELECTED COMPOUNDS | GPR119, GPR65, GPR84 | SMN1; SMN2 2497/4885TSHR 300/4885GAA 2267/4885 |
| US-20190262311-A1 | PYRIDYL SUBSTITUTED INDOLE COMPOUNDS | TLR7, TLR9, TLR1 | SMN1; SMN2 3902/4885TSHR 541/4885GAA 4741/4885 |
| US-20150353582-A1 | NORBORNENYLHYDROCARBYLENE DIHYDROCARBYLBORANES AND METHODS OF MAKING THE SAME | CYP8B1, BDKRB1, CYP1B1 | SMN1; SMN2 2340/4885TSHR 2733/4885GAA 4768/4885 |
| US-10660877-B2 | Pyridyl substituted indole compounds | TLR7, TLR9, TLR1 | SMN1; SMN2 3902/4885TSHR 541/4885GAA 4741/4885 |
| US-20170296539-A1 | COMPOSITE PREPARATION, CONTAINING NOVEL 3-(4--(BENZYLOXY)PHENYL)HEX-4-INOIC ACID DERIVATIVE AND ANOTHER ACTIVE INGREDIENT, FOR PREVENTING OR TREATING METABOLIC DISEASES | SLC5A2, SLC5A1, DPP4 | SMN1; SMN2 2750/4885TSHR 2311/4885GAA 112/4885 |
| US-11833229-B2 | Labeling precursors with squaric acid coupling | SCLY, SRRT, CS | SMN1; SMN2 1919/4885TSHR 149/4885GAA 37/4885 |
| US-20110207934-A1 | PYRIDINE BORANE COMPLEXES | NBAS, BRD8, PAXBP1 | SMN1; SMN2 3809/4885TSHR 3483/4885GAA 4566/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.