Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9439689 | 0.76 | TSHR (0.47) | ALDH1A1LMNATP53TSHR | |
| SCHEMBL13324558 | 0.76 | TSHR (0.47) | ALDH1A1LMNATP53TSHR | |
| SCHEMBL15066 | 0.76 | — | — | |
| SCHEMBL20278839 | 0.76 | TSHR (0.47) | ALDH1A1LMNATP53TSHR | |
| SCHEMBL8832603 | 0.76 | TSHR (0.47) | ALDH1A1LMNATP53TSHR | |
| SCHEMBL14717601 | 0.73 | — | — | |
| SCHEMBL8984959 | 0.73 | — | — | |
| SCHEMBL8984924 | 0.73 | — | — | |
| SCHEMBL15385183 | 0.71 | TSHR (0.37) | ALDH1A1LMNATP53TSHR | |
| Cyclopropane SCHEMBL17923269 | 0.70 | ALDH1A1 (0.41) | ALDH1A1LMNATP53TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8927682-B2 | Functionalization of polyglycolides by “click” chemistry | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2015-01-06 | — | — | US | disclosed |
| WO-2009029242-A1 | FUNCTIONALIZATION OF POLYGLYCOLIDES BY 'CLICK' CHEMISTRY | MICHIGAN STATE UNIVERSITY (US) | 2009-03-05 | — | — | WO | disclosed |
| US-20090054619-A1 | Functionalization of polyglycolides by \"click\" chemistry | BOARD OF TRUSTEES OF MICHIGAN STATE UNIVERSITY (US) | 2009-02-26 | — | — | US | disclosed |