Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.58 |
| ▸ | HPGD | P15428 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 4/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.45 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | PDE4A | P27815 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7455846 | 0.87 | MAPT (0.53) | HSD17B10HPGDALOX15MAPTKDM4E | |
| SCHEMBL733385 | 0.84 | HSD17B10 (0.59) | HSD17B10HPGDALOX15MAPTKDM4E | |
| SCHEMBL1255394 | 0.82 | HSD17B10 (0.58) | HSD17B10HPGDALOX15MAPTKDM4E | |
| SCHEMBL69868 | 0.80 | HSD17B10 (0.76) | HSD17B10HPGDALOX15MAPTKDM4E | |
| SCHEMBL29437924 | 0.80 | HSD17B10 (0.76) | HSD17B10HPGDALOX15MAPTKDM4E | |
| SCHEMBL4528196 | 0.79 | HSD17B10 (0.58) | HSD17B10HPGDALOX15MAPTKDM4E | |
| Bicarbonate SCHEMBL27452806 | 0.78 | HSD17B10 (0.73) | HSD17B10HPGDALOX15MAPTKDM4E | |
| Methane SCHEMBL27316738 | 0.78 | HSD17B10 (0.73) | HSD17B10HPGDALOX15MAPTKDM4E | |
| Phosphine SCHEMBL28084508 | 0.78 | HSD17B10 (0.73) | HSD17B10HPGDALOX15MAPTKDM4E | |
| Hydrogen Sulfide SCHEMBL28157119 | 0.78 | HSD17B10 (0.73) | HSD17B10HPGDALOX15MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110678450-B | Isoxazole derivatives as nuclear receptor agonists and uses thereof | 日东制药株式会社 | 2023-06-20 | — | — | CN | disclosed |
| EP-1457511-B1 | CROSSLINKABLE AROMATIC RESINS HAVING PROTONIC ACID GROUPS AND ION CONDUCTIVE POLYMER MEMBRANES BINDERS AND FUEL CELLS MADE BY USING THE SAME | MITSUI CHEMICALS INC (JP) | 2009-07-15 | — | — | EP | disclosed |
| CN-100462389-C | Crosslinkable aromatic resin having protonic acid group, and ion conductive polymer membrane, binder and fuel cell using the resin | MITSUI CHEMICALS INC (JP) | 2009-02-18 | — | — | CN | disclosed |
| US-7345135-B2 | Crosslinkable aromatic resin having protonic acid group, and ion conductive polymer membrane, binder and fuel cell using the resin | MITSUI CHEMICALS, INC. (JP) | 2008-03-18 | — | — | US | disclosed |
| CN-1630676-A | Crosslinkable aromatic resin having protonic acid group, and ion conductive polymer membrane, binder and fuel cell using the resin | MITSUI CHEMICALS INC (JP) | 2005-06-22 | — | — | CN | disclosed |
| US-20040191602-A1 | Crosslinkable aromatic resin having protonic acid group, and ion conductive polymer membrane, binder and fuel cell using the resin | MITSUI CHEMICALS, INC. (JP) | 2004-09-30 | — | — | US | disclosed |
| EP-1457511-A1 | CROSSLINKABLE AROMATIC RESINS HAVING PROTONIC ACID GROUPS AND ION CONDUCTIVE POLYMER MEMBRANES BINDERS AND FUEL CELLS MADE BY USING THE SAME | Mitsui Chemicals, Inc. (JP) | 2004-09-15 | — | — | EP | disclosed |